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Activated protein C differentially regulates both viability and differentiation of osteoblasts mediated by bisphosphonates

Lee YJ, Jeong JK, Seol JW, Xue M, Jackson C, Park SY

  • KMID: 2154228
  • Exp Mol Med.
  • 2013 Feb;45(2):e9.
Activated protein C (APC) is a cytoprotective anticoagulant that can promote cutaneous healing. We examined the effect of APC on viability and differentiation of the osteoblastic line, MG63, in the...
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Refractory Hypertension and Isosexual Pseudoprecocious Puberty Associated with Renin-Secreting Ovarian Steroid Cell Tumor in a Girl

Lee SH, Kang MS, Lee GS, Chung WY

Steroid cell tumor, not otherwise specified (NOS), are rare ovarian tumor, in addition, it is more rare in children. The majority of these tumors produce several steroid hormones, particularly testosterone....
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Rapid Isolation of Adipose Tissue-Derived Stem Cells by the Storage of Lipoaspirates

Eom YW, Lee JE, Yang MS, Jang IK, Kim HE, Lee DH, Kim YJ, Park WJ, Kong JH, Shim KY, Lee JI, Kim HS

PURPOSE: This study examined a rapid isolation method decreasing the time and cost of the clinical application of adipose tissue-derived stem cells (ASCs). MATERIALS AND METHODS: Aliquots (10 g) of the...
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Differential inhibition of endothelial cell proliferation and migration by urokinase subdomains: amino-terminal fragment and kringle domain

Kim KS, Hong YK, Lee Y, Shin JY, Chang SI, Chung SI, Joe YA

  • KMID: 1119342
  • Exp Mol Med.
  • 2003 Dec;35(6):578-585.
The serine protease urokinase-type plasminogen activator (uPA) is implicated in pericellular proteolysis in a variety of physiological and pathological processes including angiogenesis and tumor metastasis. The kringle domain of uPA...
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IL-12-STAT4-IFN-gamma axis is a key downstream pathway in the development of IL-13-mediated asthma phenotypes in a Th2 type asthma model

Kim YS, Choi SJ, Choi JP, Jeon SG, Oh SY, Lee BJ, Gho YS, Lee CG, Zhu Z, Elias JA, Kim YK

IL-4 and IL-13 are closely related cytokines that are produced by Th2 cells. However, IL-4 and IL-13 have different effects on the development of asthma phenotypes. Here, we evaluated downstream...
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