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Antinociceptive Effects of Intrathecal Adenosine Receptors Subtype Agonists in the Formalin Test

Yoon MH, Bae HB, Park HC, Choi JC, Choi JI

BACKGROUND: Adenosine has shown an antinociceptive action, which is mediated via spinal adenosine receptors. Previous studies have revealed the presence of four subtypes of adenosine receptor, A1, A2A, A2B and...
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Sleep Promoting Effect of Luteolin in Mice via Adenosine A1 and A2A Receptors

Kim TH, Custodio R, Cheong JH, Kim HJ, Jung YS

Luteolin, a widespread flavonoid, has been known to have neuroprotective activity against various neurologic diseases such as epilepsy, and Alzheimer’s disease. However, little information is available regarding the hypnotic effect...
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Polydeoxyribonucleotide, as a Novel Approach for the Management of Medication-Related Osteonecrosis of the Jaw: A Preliminary Observational Study

Jung J, Lim HS, Lee DW

PURPOSE: Polydeoxyribonucleotide (PDRN), consisting of a mixture of deoxyribonucleotide polymers, has been suggested to have anti-inflammatory effects and enhance angiogenesis as an adenosine A(2A) receptor agonist. The aim of this...
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Microarray Analysis of Gene Expression in Rat Glioma after Ethanol Treatment

Lee SH, Oh DY, Han JH, Choi IG, Jeon YW, Lee JN, Lee TK, Jeong JH, Jung KH, Chai YG

  • KMID: 2249214
  • Korean J Biol Psychiatry.
  • 2007 May;14(2):115-121.
Objetives: Identification of target genes for ethanol in neurons is important for understanding its molecular and cellular mechanism of action and the neuropathological changes seen in alcoholics. The purpose of...
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Effect of Polydeoxyribonucleotide on Lipopolysaccharide and Sevoflurane-Induced Postoperative Cognitive dysfunction in Human Neuronal SH-SY5Y Cells

Jeong H, Chung JY, Ko IG, Kim SH, Jin JJ, Hwang L, Moon EJ, Lee BJ, Yi JW

PURPOSE: Postoperative cognitive dysfunction (POCD) is a complication of surgery characterized by acute cognitive dysfunction, memory impairment, and loss of attention. The effect of polydeoxyribonucleotide (PDRN) on the POCD environment...
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