- Association between Recent Acetaminophen Use and Asthma: Modification by Polymorphism at TLR4
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Lee SH, Kang MJ, Yu HS, Hong K, Jung YH, Kim HY, Seo JH, Kwon JW, Kim BJ, Kim HJ, Kim YJ, Kim HS, Kim HB, Park KS, Lee SY, Hong SJ
- KMID: 1786107
- J Korean Med Sci.
- 2014 May;29(5):662-668.
- doi: 10.3346/jkms.2014.29.5.662
The risk of asthma has been increasing in parallel with use of acetaminophen, which is a potential source of oxidative stress. Toll-like receptor 4 (TLR4) plays a critical role not... -
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- Rottlerin enhances IL-1beta-induced COX-2 expression through sustained p38 MAPK activation in MDA-MB-231 human breast cancer cells
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Park EJ, Kwon TK
- KMID: 1058704
- Exp Mol Med.
- 2011 Dec;43(12):669-675.
- doi: 10.3858/emm.2011.43.12.077
Cyclooxygenase-2 (COX-2) is an important enzyme in inflammation. In this study, we investigated the underlying molecular mechanism of the synergistic effect of rottlerin on interleukin1beta (IL-1beta)-induced COX-2 expression in MDA-MB-231... -
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