Skip Navigation
Skip to contents
Results by Year

View Wide

Filter

ARTICLE TYPE

more+
SELECT FILTER
 
Close

PUBLICATION DATE

468 results
Display

Medial prefrontal cortex nitric oxide modulates neuropathic pain behavior through mu opioid receptors in rats

Raisian D, Erfanparast A, Tamaddonfard E, Soltanalinejad-Taghiabad F

Background: The neocortex, including the medial prefrontal cortex (mPFC), contains many neurons expressing nitric oxide synthase (NOS). In addition, increasing evidence shows that the nitric oxide (NO) and opioid systems...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Impact of polystyrene microplastic exposure on lipid profile and oxidative stress status of male and female Wistar rats

Nnoruka UC, Okonkwo CJ, Ilechukwu I, Okonkwo CJ, Belonwu DC

Microplastics (MPs) are currently global environmental pollutants, and their associated health risks cannot be ignored. However, research on MP toxicity in mammals is limited. We investigated the effects of polystyrene...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Chronic toxic effects of polystyrene microplastics on reproductive parameters of male rats

Ilechukwu I, Ehigiator BE, Ben IO, Okonkwo CJ, Olorunfemi OS, Modo UE, Ilechukwu CE, Ohagwa NJ

Microplastics have become a significant environmental concern. However, information on toxicity of microplastics in terrestrial organisms is limited. In this study, the chronic toxic effects of polystyrene microplastics (PS-MPs) on...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Deep learning approach for classification of chondrocytes in rats

Kang JS

The rapid development of computer vision and deep learning has enabled these technologies to be applied to the automated classification and counting of microscope images, there-by relieving of some burden...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Peripheral Neuropathy Phenotyping in Rat Models of Type 2 Diabetes Mellitus: Evaluating Uptake of the Neurodiab Guidelines and Identifying Future Directions

Hossain MJ, Kendig MD, Letton ME, Morris MJ, Arnold R

Diabetic peripheral neuropathy (DPN) affects over half of type 2 diabetes mellitus (T2DM) patients, with an urgent need for effective pharmacotherapies. While many rat and mouse models of T2DM exist,...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of cyanocobalamin and its combination with morphine on neuropathic rats and the relationship between these effects and thrombospondin-4 expression

Düzenli N, Ülker S, Şengül G, Kayhan B, Önal A

Background: Thrombospondin-4 (TSP4) upregulates in the spinal cord following peripheral nerve injury and contributes to the development of neuropathic pain (NP). We investigated the effects of cyanocobalamin alone or in combination...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Pharmacological interactions between intrathecal pregabalin plus tianeptine or clopidogrel in a rat model of neuropathic pain

Lee HG, Kim YO, Choi JI, Han XH, Shin YU, Yoon MH

Background: There is still unmet need in treating neuropathic pain and increasing awareness regarding the use of drug combinations to increase the effectiveness of treatment and reduce adverse effects in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Anti-nociceptive and anti-inflammatory activities of the essential oil isolated from Cupressus arizonica Greene fruits

Fakhri S, Jafarian S, Majnooni MB, Farzaei MH, Mohammadi-Noori E, Khan H

Background: Cupressus arizonica Greene is a coniferous tree with great importance in fragrance and pharmaceutical industries. Essential oils from C. arizonica (EC) have shown potential antioxidant, and anti-microbial activities. This...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
The role of basolateral amygdala orexin 1 receptors on the modulation of pain and psychosocial deficits in nitroglycerin-induced migraine model in adult male rats

Askari-Zahabi K, Abbasnejad M, Kooshki R, Raoof M, Esmaeili-Mahani S, Pourrahimi AM, Zamyad M

Background: Migraine headaches have been associated with sensory hyperactivity and anomalies in social/emotional responses. The main objective of this study was to evaluate the potential involvement of orexin 1 receptors...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Fecal Microbial Enterotypes Differentially Respond to a High-fat Diet Based on Sex in Fischer-344 Rats

Choi SI, Kim N, Nam RH, Park JH, Nho H, Yu JE, Song CH, Lee SM, Lee DH

The gut microbiota interacts with the host gut environment, which is influenced by such factors as sex, age, and host diet. These factors induce changes in the microbial composition. The...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Validation of the Thyrotoxicosis-associated Insomnia Model Induced by Thyroxine through Sympathetic Stimulation: Face, Construct and Predictive Perspectives

Ai Z, He H, Wang T, Chen L, Huang C, Chen C, Xu P, Zhu G, Yang M, Song Y, Su D

  • KMID: 2524036
  • Exp Neurobiol.
  • 2021 Dec;30(6):387-400.
  • doi: 10.5607/en21023
Insomnia has become a common central nervous system disease. At present, the pathogenesis of insomnia is not clear. Animal models can help us understand the pathogenesis of the disease and...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Anti-diabetic effects of aqueous extract of Dendropanax morbifera Lev. leaves in streptozotocin-induced diabetic Sprague-Dawley rats

Kim MJ, Kang YJ, Lee DE, Kim S, Lim SH, Lee HJ

This study examined the anti-diabetic effects of aqueous extracts of Dendropanax morbifera leaves (DMWEs) in streptozotocin-induced diabetic Sprague-Dawley (SD) rats. Thirty male SD rats (body weight [BW], 250.4 ± 19.7...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Adipose tissue-derived mesenchymal stem cells reduce endometriosis cellular proliferation through their anti-inflammatory effects

Meligy FY, Elgamal DA, Abdelzaher LA, Khashbah MY, El-Mokhtar MA, Sayed AA, Refaiy AM, Othman ER

Objective: Endometriosis is a chronic debilitating inflammatory condition characterized by the presence of endometrial tissues outside the uterine cavity. Pelvic soreness and infertility are the usual association. Due to the...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of Different Types of Mechanical Loading on Trabecular Bone Microarchitecture in Rats

Ju YI, Sone T

Mechanical loading is generally considered to have a positive impact on the skeleton; however, not all types of mechanical loading have the same beneficial effect. Many researchers have investigated which...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Investigation of Thiol/Disulfide Balance in Obese Rats with Non-Alcoholic Fatty Liver Disease

Tursun S, Gülerman HF, Gazyağcı S, Şahin Y, Erel , Neşelioğlu S

Purpose: Due to the increasing prevalence of obesity worldwide, non-alcoholic fatty liver disease (NAFLD) has reached epidemic dimensions over time. NAFLD is the most common cause of childhood chronic liver...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Estrogen modulates epithelial progenitor cells in rat vagina

Chung HS, Lee HS, Park K

Purpose: The expression of epithelial progenitor cells (EPCs) in rat vagina was recently reported. The aims were to investigate the effects of estrogen on vaginal EPCs in the oophorectomized female...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
A novel excisional wound pain model for evaluation of analgesics in rats

Parra S, Thanawala VJ, Rege A, Giles H

Background: Management of pain from open wounds is a growing unmet healthcare need. However, the models available to study pain from wounds or to develop analgesics for the patients suffering...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Effects of Recombinant Human Growth Hormone on the Onset of Puberty, Leydig Cell Differentiation, Spermatogenesis and Hypothalamic KISS1 Expression in Immature Male Rats

Huh K, Nah WH, Xu Y, Park MJ, Gye MC

Purpose: Recombinant human growth hormone (rhGH) has been used to treat short stature and rhGH-related syndromes. However, there are concerns that rhGH-treatment may cause precocious puberty. We investigated the effects...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Feeding pattern, biochemical, anthropometric and histological effects of prolonged ad libitum access to sucrose, honey and glucose-fructose solutions in Wistar rats

Virgen-Carrillo CA, Martínez Moreno AG, Rodríguez-Gudiño JJ, Pineda-Lozano JE

BACKGROUND/OBJECTIVES: The exposure to sucrose in rats has mimic abnormalities attributed to metabolic syndrome (MetS). The effects of honey bee and “free” glucose and fructose, have not been explored in...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close
Comparison of Intravesical Hyaluronic Acid, Chondroitin Sulfate, and Combination of Hyaluronic Acid-Chondroitin Sulfate Therapies in Animal Model of Interstitial Cystitis

Danacioglu YO, Erol B, Ozkanli S, Yildirim A, Atis RG, Silay MS, Caskurlu T

Purpose: Three intravesical treatment agents were compared in an interstitial cystitis rat model: chondroitin sulfate, hyaluronic acid, and combined hyaluronic acid-chondroitin sulfate. Methods: Thirty-five female rats were divided into 5 groups:...
CITED
export Copy
Close
SHARE
Twitter Facebook
Close

Go to Top

Copyright © 2022 by Korean Association of Medical Journal Editors. All rights reserved.     E-mail: koreamed@kamje.or.kr