- Nonmotor and Dopamine Transporter Change in REM Sleep Behavior Disorder by Olfactory Impairment
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Lee JY, Yoon EJ, Kim YK, Shin CW, Nam H, Jeong JM, Kim HJ, Jeon B
- KMID: 2449682
- J Mov Disord.
- 2019 May;12(2):103-112.
- doi: 10.14802/jmd.18061
OBJECTIVE: It is unclear whether the decline in dopamine transporters (DAT) differs among idiopathic rapid eye movement sleep behavior disorder (iRBD) patients with different levels of olfactory impairment. This study... -
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- The Effect of SSRIs on the Binding of 18F-FP-CIT in Parkinson Patients: A Retrospective Case Control Study
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Seo M, Oh M, Cho M, Chung SJ, Lee CS, Kim JS
- KMID: 2313211
- Nucl Med Mol Imaging.
- 2014 Dec;48(4):287-294.
- doi: 10.1007/s13139-014-0286-0
PURPOSE: 18F-FP-CIT [18F-fluorinated N-3-fluoropropyl-2-beta-carboxymethoxy-3-beta-(4-iodophenyl) nortropane] is useful for detecting striatal dopamine transporter (DAT). Since FP-CIT shows relatively high affinities for DAT and serotonin transporter (SERT), its binding can be influenced... -
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- Normal Sleep in Children and Adolescents
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Nam SO
- KMID: 1442105
- J Korean Child Neurol Soc.
- 2011 Aug;19(2):67-75.
Sleep is not just a rest for brain activity during daytime, but also has a vital function for memory consolidation after learning as well as restoration of both body and... -
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- 5-hydroxy-L-tryptophan Suppressed Food Intake in Rats Despite an Increase in the Arcuate NPY Expression
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Moon YW, Choi SH, Yoo SB, Lee JH, Jahng JW
- KMID: 1460757
- Exp Neurobiol.
- 2010 Dec;19(3):132-139.
- doi: 10.5607/en.2010.19.3.132
This study was conducted to define the underlying mechanism of hypophagia induced by increased central serotonergic action. Rats received 3 daily injections of 5-hydroxy-L-tryptophan (5-HTP), a serotonin precursor, at a... -
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- Effect of Electroacupuncture on Visceral Hyperalgesia, Serotonin and Fos Expression in an Animal Model of Irritable Bowel Syndrome
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Wu JC, Ziea ET, Lao L, Lam EF, Chan CS, Liang AY, Chu SL, Yew DT, Berman BM, Sung JJ
- KMID: 2326165
- J Neurogastroenterol Motil.
- 2010 Jul;16(3):306-314.
BACKGROUND/AIMS: While it is well established that acupuncture relieves somatic pain, its therapeutic effect on visceral pain such as irritable bowel syndrome (IBS) is unclear. We evaluated the effect of... -
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- Vardenafil Increases Cell Proliferation in the Dentate Gyrus through Enhancement of Serotonin Expression in the Rat Dorsal Raphe
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Kim TS, Ko IG, Sung YH, Kim SE, Kim BK, Park SK, Shin MS, Kim CJ, Yoon SJ, Kim KH
- KMID: 1783139
- J Korean Med Sci.
- 2009 Dec;24(6):1099-1104.
- doi: 10.3346/jkms.2009.24.6.1099
This study was conducted to evaluate the effects of vardenafil (Levitra), a phosphodiesterase-5 (PDE-5) inhibitor, on cell proliferation in the hippocampal dentate gyrus and on 5-hyroxytryptamine (5-HT, serotonin) synthesis and... -
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- Immunohistochemical Study on the Distribution of Kv1.2 in Aged Rat Brain
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Chung YH, Kim SS, Kim KY, Lee WB
- KMID: 2376074
- Korean J Phys Anthropol.
- 2007 Jun;20(2):137-144.
In the present study, we demonstrated age-related changes in Kv1.2 immunoreactivity in the rat brain for the first time. Twelve adult (4~6 month old) and 15 aged (20~29 month old)... -
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- Neuroanatomy of Sleep-Wake Regulation and its Application to Pharmacotherapy
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Kim HC
- KMID: 2286720
- Korean J Psychopharmacol.
- 2007 May;18(3):133-142.
A current hypothesis of sleep-wake regulation proposes that the sleep process starts with the activation of sleep-promoting neurons located in the preoptic area of the anterior hypothalamus. This activation leads... -
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- Effect of Exogenous Thyroxine on the Postnatal Development of Serotonin-containing Neuron in Fetal Alcohol Effects in the Rat Raphe Nuclei
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Chung YY, Kim JS, Kim JJ
- KMID: 1512986
- Korean J Phys Anthropol.
- 2006 Mar;19(1):25-35.
Serotonin (5-hydroxytryptamine, 5-HT) has been concerned in the pathophysiology of various neuropsychiatric disorders. It is known to modulate emotion, cognition, endocrine activity, motor function, and pain. In the present study,... -
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- Elevated Serotonin-immunoreactive Neurons in the Raphe Nucleus of the Ataxic Mutant Mouse, Pogo
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Kim CT, Han SY, Jeong JH, Yoon DS, Lee S, Hawkes R, Lee NS, Jeong YG
- KMID: 2092857
- Korean J Anat.
- 2005 Oct;38(5):395-402.
This study was carried out to investigate the distribution of serotonin-immunoreactive neruons in the raphe nucleus of the ataxic pogo (pogo/pogo) mice derived from a Korean wild mice. Using by... -
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- 5-Hydroxytryptamine Inhibits Glutamatergic Synaptic Transmission in Rat Corticostriatal Brain Slice
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Cho HS, Choi SJ, Kim KJ, Lee HH, Kim SY, Cho YJ, Sung KW
- KMID: 1600107
- Korean J Physiol Pharmacol.
- 2005 Oct;9(5):255-262.
Striatum is involved in the control of movement and habitual memory. It receives glutamatergic input from wide area of the cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT)... -
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- Understanding Stress by Neuroscience
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Yoon SJ, Kim TS, Chae JH
- KMID: 2294656
- J Korean Acad Fam Med.
- 2005 Aug;26(8):439-450.
Stress can be defined generally as reponses to stressors on the body or in a definition more focused on the central nervous system, it can be defined as alterations in... -
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- Serotonin transporter mRNA expression in the dorsal raphe nucleus of a tumor bearing mouse
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Jahng JW, Choi SH, Cha MJ, Kim NY, Hwang SJ, Lee JH
- KMID: 1033103
- Exp Mol Med.
- 2005 Feb;37(1):65-69.
This study was conducted to determine if an oral squamous cell carcinoma alters mRNA expression of serotonin transporter (5-HTT) in the central nervous system. KB cell line derived from a... -
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- Effects of Chronic Alcohol Exposure on Dopaminergic and Serotonergic Neurotransmission System in Rat
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Park SW, Lee YC, Ha EK, Kim YK, Lee YK, Chung DO, Ryu JW, Kong BG, Kim YH
- KMID: 2287358
- Korean J Psychopharmacol.
- 2005 Jan;16(1):81-90.
OBJECTIVE: This study investigates the effects of chronic alcohol exposure on rat brain THmRNA expression, TH (tyrosine hydroxylase) acitivity, and TPH (tryptophan hydroxylase) activity which are important in synthesis of... -
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- The Effect of Melatonin Injection into Rat Brain Stem with Chronic Stress on Serotonergic Immunoreactivity
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Kim MS
- KMID: 1609555
- Korean J Phys Anthropol.
- 2004 Dec;17(4):321-330.
These experiments were performed to investigate the effect of saline, melatonin, stress, stressed-melatonin on serotonin immunoreactivity in rat brain stem. The animals were injected with melatonin (1 mg/kg, i.p.) after... -
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- Localization of Nerves Innervating the Sublingual Gland in the Rat Brain Using Pseudorabies Virus
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Han EH, Kim KA, Lee CH
- KMID: 1609463
- Korean J Phys Anthropol.
- 2004 Sep;17(3):197-205.
The nerves innervating the sublingual gland of the rat was investigated using PRV (pseudorabies virus) as a neural tracer. The neural tracer was injected into left sublingual gland of the... -
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- The Effect of Photoperiod and Melatonin Injection on Serotonergic Immunoreactivity in Rat Brain Stem
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Kim MS, Jeon SW, Lee CH
- KMID: 2224521
- Korean J Anat.
- 2003 Dec;36(6):537-547.
These experiments were performed to investigate the effect of photoperiod and melatonin on serotonergic immunoreactivity in rat brain stem. The animals were injected with melatonin (1 mg/kg, i.p.) after light... -
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- Inhibitory Modulation of 5-Hydroxytryptamine on Corticostriatal Synaptic Transmission in Rat Brain Slice
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Choi SJ, Chung WS, Kim KJ, Sung KW
- KMID: 1607512
- Korean J Physiol Pharmacol.
- 2003 Dec;7(6):295-301.
Striatum plays a crucial role in the movement control and habitual learning. It receives an information from wide area of cerebral cortex as well as an extensive serotonergic (5-hydroxytryptamine, 5-HT)... -
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- Acute Effect of Alcohol and Nicotine on 5-Hydroxytryptamine Synthesis and Tryptophan Hydroxylase Expression in Dorsal and Median Raphe of Rats
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Jang MH, Shin MC, Chang HK, Lee TH, Kim KH, Kim YJ, Kim CJ
- KMID: 1607347
- Korean J Physiol Pharmacol.
- 2003 Feb;7(1):5-8.
Alcohol abuse and cigarette smoking have been on the rise worldwide and it has been reported that alcohol and nicotine influence serotonergic neuronal activity in the dorsal raphe. Serotonin (5-hydroxytryptamine,... -
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- The Effect of Treatment with Imipramine and/or Tryptophan after Chronic Stress on the Serotonergic Immunoreactivity in Rat Raphe Nucleus
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Kim MS, Lee CH
- KMID: 1559383
- Korean J Anat.
- 2002 Oct;35(5):453-462.
These experiments were performed to investigate the effect of saline, stress, imipramine, stress -imipramine and/or stress -tryptophan on serotonin immunoreactivity in raphe nucleus of the rats (200 ~220 g, body... -
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