- The effects of naringenin and naringin on the glucose uptake and AMPK phosphorylation in high glucose treated HepG2 cells
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Dayarathne LA, Ranaweera SS, Natraj P, Rajan P, Lee YJ, Han CH
- KMID: 2522875
- J Vet Sci.
- 2021 Nov;22(6):e92.
- doi: 10.4142/jvs.2021.22.e92
Background: Naringin and its aglycone naringenin are citrus-derived flavonoids with several pharmacological effects. On the other hand, the mechanism for the anti-diabetic effects of naringenin and naringin are controversial and... -
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- Anti-adipogenic effect of the flavonoids through the activation of AMPK in palmitate (PA)-treated HepG2 cells
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Rajan P, Natraj P, Ranaweera SS, Dayarathne LA, Lee YJ, Han CH
- KMID: 2525538
- J Vet Sci.
- 2022 Jan;23(1):e4.
- doi: 10.4142/jvs.21256
Objectives: The present study observed the anti-adipogenic effects of five major citrus flavonoids, including hesperidin (HES), narirutin (NAR), nobiletin (NOB), sinensetin (SIN), and tangeretin (TAN), on AMP-activated protein kinase (AMPK)... -
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- Anti-inflammatory effect of sulforaphane on LPS-stimulated RAW 264.7 cells and ob/ob mice
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Ranaweera SS, Dissanayake CY, Natraj P, Lee YJ, Han CH
- KMID: 2509148
- J Vet Sci.
- 2020 Nov;21(6):e91.
- doi: 10.4142/jvs.2020.21.e91
Background: Sulforaphane (SFN) is an isothiocyanate compound present in cruciferous vegetables. Although the anti-inflammatory effects of SFN have been reported, the precise mechanism related to the inflammatory genes is poorly... -
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- Restoration of the adipogenic gene expression by naringenin and naringin in 3T3-L1 adipocytes
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Dayarathne LA, Ranaweera SS, Natraj P, Rajan P, Lee YJ, Han CH
- KMID: 2518801
- J Vet Sci.
- 2021 Jul;22(4):e55.
- doi: 10.4142/jvs.2021.22.e55
Background: Naringenin and its glycoside naringin are well known citrus flavonoids with several therapeutic benefits. Although the anti-adipogenic effects of naringenin and naringin have been reported previously, the detailed mechanism... -
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