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Effects of Ramipril on Vascular Response in Patients with Coronary Artery Disease

Cho BK, Park KR, Kim KY, Bae JH

BACKGROUND AND OBJECTIVES: Angiotensin-converting enzyme (ACE) inhibitors have been shown to improve the endothelial dysfunction and prevent the development of atherosclerosis in animal models. We performed this study to investigate...
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Hypotensive Efficacy and Safety of Ramipril on the Patients with Essential Hypertension

Yoo WS, Kwon SW, Lim CY, Park SH, Choi SK, Lee DC

Thirty three patients with mild to moderate essential hypertension were administered ramipril, a new ACe inhibitor, 2.5-5mg once daily for 6 weeks to evaluate the hypotensive efficacy and safety. The...
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J-curve Phenomenon Might Be Inherent: How to Know If It Is Treatment Induced?

Shin J

No abstract available.
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Antihypertensive Effect of Ramipril in Patients with Essential Hypertension

Song JS, Kim YS, Cheong HJ, Kang HS, Choue CW, Kim KS, Kim MS, Bae JH

BACKGROUND: Angiotensin converting enzyme(ACE) inhibition as a means of controlling blood pressure began in the 1970s. This increasing knowledge of ACE inhibitors has resulted in their being used with confidence...
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The Additive Beneficial Effects of Ramipril Combined with Candesartan in Hypertensive Patients on Insulin Resistance, Plasma Adiponectin

Han SH, Lee SJ, Oh BC, Koh KK, Shin EK

BACKGROUND AND OBJECTIVES: Ramipril and candesartan have decreased the incidence of new onset diabetes in large scale randomized clinical studies. Because ramipril and candesartan have distinct mechanisms of action in...
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The Phase 4 Randomized, Public, Parallel, Comparative, Clinical Trial to Compare Efficacy and Safety of S-(-)-Amlodipine Nicotinate with Ramipril in Hypertensive Patients

Kim MS, Jeong MH, Lee MG, Sim DS, Park KH, Yoon NS, Yoon HJ, Kim KH, Hong YJ, Kim JH, Ahn YK, Cho JG, Park JC, Kang JC

BACKGROUND: The aim of this study was to compare the antihypertensive effect of S-(-)-amlodipine nicotinate with ramipril in patients with essential hypertension. METHODS: Total 138 patients (54.5 +/- 10.5 years, 69...
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A Case of Severe Prolonged Hypoglycemia Caused by Combined Ramipril and Amiloride Treatment in a Nondiabetic Woman

Cho MH, Kim DM, Kim CS, Park JS, Nam JY, Chang JH, Park J, Ahn CW, Cha BS, Lim SK, Kim KR, Lee HC

  • KMID: 2008184
  • J Korean Diabetes Assoc.
  • 2004 Dec;28(6):554-557.
The relationship between angiotensin converting enzyme inhibition and hypoglycemia remains controversial. An 82-year-old, nondiabetic woman who had taken ramipril 5 mg with amiloride 5 mg for two months was admitted...
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Comparison of endothelial function improvement estimated with reactive hyperemia index between ramipril and telmisartan in hypertensive patients

Ki YJ, Seo JB, Kim HL, Lim WH, Seo HY, Lee JY, Chung WY

BACKGROUND: Endothelium has a function to regulate vascular tone by releasing mediators either vasodilating or vasoconstricting blood vessels. Endothelial dysfunction can be measured conveniently by Reactive Hyperemia Index (RHI) with...
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The long-term effect of ramipril on Gialpha2-protein and Protein Tyrosine Phosphatase 1B in an animal model of type 2 diabetes(OLETF rat)

Lee JM, Hong OK, Kwon HS, Moon SD, Chang SA, Son HS, Yoon KH, Cha BY, Kang SK

  • KMID: 2331782
  • J Korean Diabetes Assoc.
  • 2006 Jan;30(1):25-38.
BACKGROUND: The regulation of tyrosine phosphorylation/dephosphorylation is an important mechanism in various intracellular metabolism. Also impaired insulin signal transduction is important in pathogenesis of type 2 diabetes. It has been...
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The Effects of Combination Therapy of Felodipine and Ramipril on Plaque Regression and Plaque Compositional Changes in Patients with Hypertension and Angina with Mild to Moderate Degree of Coronary Stenosis

Hong YJ, Jeong MH, Choi YH, Ma EH, Ko JS, Lee MG, Park KH, Sim DS, Yoon NS, Yoon HJ, Kim KH, Park HW, Kim JH, Ahn Y, Cho JG, Park JC, Kang JC

  • KMID: 2330954
  • J Korean Soc Hypertens.
  • 2010 Mar;16(1):31-42.
BACKGROUND: Calcium channel blockers (CCB) and angiotensin converting enzyme (ACE) inhibitors can block the development of atherosclerosis. Fixed-dose combinations of a CCB, felodipine, and an ACE inhibitor, ramipril, are more...
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Musical murmur in a dog with acute chordae tendineae rupture

Min SH, Kang MH, Park HM

  • KMID: 1790575
  • Korean J Vet Res.
  • 2013 Dec;53(4):263-264.
A 6 year-old, spayed female, Maltese dog was presented with precordial thrill and mild coughing. Thoracic auscultation revealed a grade V/VI systolic murmur with maximal intensity over the left apex...
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Effects of Simvastatin Alone or Combined With Ramipril on Nitric Oxide Bioactivity and Inflammation Markers in Hypercholesterolemic Patients

Son JW, Koh KK, You SM, Ryu WS, Ahn JY, Kim HG, Kim DS, Kim HS, Oh KJ, Shin EK

BACKGROUND AND OBJECTIVES: Because the mechanisms of the biological effects of statin and antiotensin converting enzyme inhibitor therapies differ, the vascular responses to these therapies were studied in hypercholesterolemic patients. MATERIALS...
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Angiotensin-Converting Enzyme Inhibitor Ramipril Improves Coronary Microvascular Remodeling in Type II Diabetic Rats

Chang K, Baek SH, Ko SH, Yoon KH, Kim KY, Seung KB, Chae JS, Kim JH, Hong SJ, Choi KB

BACKGROUND AND OBJECTIVES: Coronary microvascular remodeling is one of the complications associated with diabetic cardiovascular disease. We investigated the effect of long-term treatment with ramipril, an angiotensin converting enzyme inhibitor,...
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The Effect of Long-term Treatment of Ramipril on Glucose Tolerance and Pancreatic Islets in Type 2 Diabetes Animal Model (OLETF Rats)

Ko SH, Yoon KH, Kim MM, Ahn YB, Song KH, Yoo SJ, Son HS, Cha BY, Lee KW, Son HY, Kang SK

  • KMID: 1568049
  • J Korean Diabetes Assoc.
  • 2001 Dec;25(6):469-482.
BACKGROUND: In a Heart Outcomes Prevention Evaluation HOPE study, ramipril, a long- acting angiotensin-converting enzyme (ACE) inhibitor, significantly reduced the death rates the number of myocardial infarctions, strokes, heart failure...
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The Comparative Clinical Effects of Valsartan and Ramipril in Patients With Heart Failure

Lee KH, Jeong MH, Ahn YK, Lee WS, Jung DH, Cho JG, Park JC, Kang JC, Oh SK, Kim NH, Yun KH, Yoo NJ, Moon Y, Rhew JY, Lim JH, Jeon SH, Park OY, Lee SU, Kang DG

BACKGROUND AND OBJECTIVES: Angiotensin II receptor blocker (ARB) has emerged as an alternative to angiotensin converting enzyme inhibitor (ACEI) for the treatment of heart failure. This study aimed at comparing...
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High Dose Ramipril Inhibits Connective Tissue Growth Factor Expression and Fibrosis in Type 2 Diabetic Rat Heart

Choi KH, Baek SH, Lee WJ, Park KN, Kim PJ, Seung KB, Chae JS, Kim JH, Choi KB

BACKGROUND AND OBJECTIVES: Connective tissue growth factor (CTGF) is a profibrotic cytokine, which may play an important role in the development of diabetic cardiovascular complications. ACE inhibition significantly prevents cardiovascular...
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Drugs in Reducing the Development of Rat Intimal Hyperplasia after Endothelial Denudatiotn

Jung SI, Cho MY, Kim YS, Yeom BW, Whang CW

  • KMID: 2198576
  • J Korean Vasc Surg Soc.
  • 1997 Nov;13(2):151-157.
Intimal hyperplasia is the universal response to endothelial denudation and occur after a variety of vascular procedures. In a proportion of cases the smooth muscle cell proliferation may lead to...
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The Correlation of Brain Natriuretic Peptide (BNP), Pulmonary Arterial Pressure, and St. George Respiratory Questionnaire (SGRQ) and Their Changes with a Trial of an Angiotensin Converting Enzyme Inhibitor

Kim MA, Kim DK, Lee CH, Chung HS

  • KMID: 2319316
  • Tuberc Respir Dis.
  • 2010 May;68(5):273-279.
BACKGROUND: Pulmonary hypertension is considered as a poor prognosis factor in patients with chronic obstructive pulmonary disease (COPD). There has been reported brain natriuretic peptide (pro-BNP) is related with increased...
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Comparison of the Antiproteinuric Effect to ACE Inhibitors in NIDDM Patients with Nephropathy According to Genotypes of ACE Gene

Yang YM, Seo JC, Lee KS, Jeon WJ, Lee HH, Jeong JB, Koong SS, Oh TG

  • KMID: 1905893
  • J Korean Diabetes Assoc.
  • 2000 Aug;24(4):476-484.
BACKGROUND: Albuminuria is a risk factor for progression of diabetic nephropathy. Antihypertensive treatment, especially angiotensin converting enzyme (ACE) inhibition, has been shown to reduce albuminuria and to ameliorate progression of...
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The Study of the Dry Cough Incidence Rate about Imidapril, the Angiotensin Converting Enzyme Inhibitor

Lee SB, Ko TY, Oh KS, Kwag JS, Chung BS, Yi KR, Choi NH, Lee JY, Kim CS

BACKGROUND AND OBJECTIVES: Imidapril, one of the ACE inhibitor, has been used to treate hypertension, congestive heart failure, diabetes mellitus and renal disease. ACE inhibitor, however often causes dry...
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