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Response to: A Randomized Control Trial Comparing Local Autografts and Allografts in Single Level Anterior Cervical Discectomy and Fusion Using a Stand-Alone Cage

Kanna RM, Perambuduri AS, Shetty AP, Rajasekaran S

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Analysis of Spinopelvic Parameters with L5 as the New Sacrum after Fusion in High-Grade Spondylolisthesis: A Possible Explanation for Satisfactory Results with In-Situ Fusion

Rajasekaran S, Das G, Aiyer SN, Kanna RM, Shetty AP

STUDY DESIGN: Retrospective case series. PURPOSE: To correlate functional outcomes with spinopelvic parameters in patients with high-grade spondylolisthesis (HGS) treated with instrumented in-situ surgery or reduction and fusion. OVERVIEW OF LITERATURE: Satisfactory...
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Circumferential Fusion through All-Posterior Approach in Andersson Lesion

Rajoli SR, Kanna RM, Aiyer SN, Shetty AP, Rajasekaran S

STUDY DESIGN: Retrospective case series. PURPOSE: To assess safety and efficacy of single stage, posterior stabilisation and anterior cage reconstruction through the transforaminal or lateral extra-cavitary route for Andersson lesions. OVERVIEW OF...
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The Effectiveness of Noninvasive Positive Pressure Ventilation in Subarachnoid Pleural Fistula: A Case Report and Literature Review

Soundararajan DCR, Shetty AP, Kanna RM, Rajasekaran S

Subarachnoid pleural fistula (SPF) is an aberrant communication between the pleural cavity and subarachnoid space, resulting in uncontrolled cerebrospinal fluid drainage. The negative pressure of the pleural cavity creates a...
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Intraoperative Life Threatening Acute Lung Injury Due to Multiple Septic Pulmonary Emboli during Transpedicular Biopsy and Kyphoplasty

Karthik K, Shetty AP, Rajasekaran S

A 55-year-old gentleman was presented to our clinic two months after a trivial fall with persistent pain, gibbus at the thoraco-lumbar junction and intact neurology. Radiological and laboratory investigations suggested...
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Impact of Acute Lumbar Disk Herniation on Sexual Function in Male Patients

Panneerselvam K, Kanna RM, Shetty AP, Rajasekaran S

Study Design: Prospective observational study. Purpose: In this study, we determined the effects of lumbar disk herniation (LDH) on male sexual activity and whether surgical intervention improved any related sexual dysfunction. Overview...
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Does Sarcopenia Increase the Risk for Fresh Vertebral Fragility Fractures?: A Case-Control Study

Anand A, Shetty AP, Renjith KR, K. S. SVA, Kanna RM, Rajasekaran S

Study Design: Case-control study. Purpose: Sarcopenia is an age associated condition characterized by decrease in muscle mass, strength, and physical performance. We aimed to investigate whether sarcopenia increased the risk of...
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Patterns of Traumatic Spinal Injuries in the Developing World: A Five-Year Longitudinal Review

Kanna RM, Peddireddy S, Shetty AP, Rajasekaran S

Study Design: Retrospective review. Purpose: A 5-year longitudinal study documenting and comparing patterns of traumatic spinal injuries (TSIs) observed in developing countries. Overview of Literature: Current knowledge of the patterns and epidemiology...
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Classification and Management Algorithm for Postoperative Wound Complications Following Transforaminal Lumbar Interbody Fusion

Kanna RM, Renjith KR, Shetty AP, Rajasekaran S

Study Design: Retrospective study. Purpose: Postoperative wound complications occurring after transforaminal lumbar interbody fusion (TLIF) are unique, as they can involve different tissue zones (subcutaneous, subfascial, osseous, peri-implant, and disc). Overview...
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Impact of Patient Counseling and Socioeconomic Factors on Initiation of Rehabilitation Program in Spinal Cord Injury Patients Presenting to a Tertiary Spine Unit in India

Aiyer SN, Gunasekaran V, Mani L, K. S. SVA, Rajasekaran S, Shetty AP

Study Design Prospective case series. Purpose This study aimed to investigate the impact of education, financial income, occupation, and patient counseling on the timing of enrolment in a spinal cord injury (SCI) rehabilitation...
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Posterior Stabilization of Unstable Sacral Fractures: A Single-Center Experience of Percutaneous Sacroiliac Screw and Lumbopelvic Fixation in 67 Cases

Shetty AP, Renjith KR, Perumal R, Anand SV, Kanna RM, Rajasekaran S

Study Design: This is a retrospective study. Purpose: Recent advances in intraoperative imaging and closed reduction techniques have led to a shifting trend toward surgical management in every unstable sacral fracture....
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Does Second-Generation Suspensory Implant Negate Tunnel Widening of First-Generation Implant Following Anterior Cruciate Ligament Reconstruction?

Sundararajan SR, Sambandam , Singh A, Rajagopalakrishnan R, Rajasekaran S

PURPOSE: Tunnel widening following anterior cruciate ligament (ACL) reconstruction is commonly observed. Graft micromotion is an important contributing factor. Unlike fixed-loop devices that require a turning space, adjustable-loop devices fit...
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Analysis of Postoperative Clinical Outcomes in Cervical Myelopathy due to Ossification of Posterior Longitudinal Ligament Involving C2

Shetty AP, Singh NA, Kalanjiyam GP, Meena J, Rajasekaran S, Kanna RM

Study Design: Retrospective study. Purpose: To investigate the radiological phenotype, patient and surgery-related risk factors influencing postoperative clinical outcome for cervical myelopathy caused by ossification of the posterior longitudinal ligament involving...
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In Vertebral Hemangiomas with Neurological Deficit, Is a Less Extensive Approach Adequate

K. GP, Shetty AP, K. S. SVA, Kavishwar R, Kanna RM, Rajasekaran S

Study Design: This was a retrospective study. Purpose: To analyze the surgical and neurological outcomes following surgical decompression in patients with aggressive vertebral hemangioma (AVH) presenting with neurological deficit and to...
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Congenital Osseous Anomalies of the Cervical Spine: Occurrence, Morphological Characteristics, Embryological Basis and Clinical Significance: A Computed Tomography Based Study

Ankith N, Avinash M, Srivijayanand K, Shetty AP, Kanna RM, Rajasekaran S

STUDY DESIGN: Observational retrospective computed tomography (CT) based study. PURPOSE: To analyze the congenital anomalies of the cervical spine, their morphological variations and their clinical significance. OVERVIEW OF LITERATURE: Studies published to...
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A Randomized Control Trial Comparing Local Autografts and Allografts in Single Level Anterior Cervical Discectomy and Fusion Using a StandAlone Cage

Kanna RM, Perambuduri AS, Shetty AP, Rajasekaran S

Study Design: Randomized controlled trial. Purpose: To compare the functional and radiological outcomes of anterior cervical discectomy and fusion (ACDF) using local graft and allograft Overview of Literature: The choice of bone...
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Motion-Preserving Navigated Primary Internal Fixation of Unstable C1 Fractures

Rajasekaran S, Soundararajan DCR, Shetty AP, Kanna RM

Study Design: Prospective observational study. Purpose: To assess the safety, efficacy, and benefits of computed tomography (CT)-guided C1 fracture fixation. Overview of Literature: The surgical management of unstable C1 injuries by occipitocervical...
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Novel Biomarkers of Health and Degeneration in Human Intervertebral Discs: In-depth Proteomic Analysis of Collagen Framework of Fetal, Healthy, Scoliotic, Degenerate, and Herniated Discs

Rajasekaran S, Soundararajan DCR, Nayagam SM, Tangavel C, Raveendran M, K S SVA, Shetty AP, Kanna RM

Study Design: Profiling proteins expressed in the nucleus pulposus (NP) of intervertebral discs (IVDs) in five different biological states. Purpose: To evaluate the molecular complexity of the collagen (COL) framework and...
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Type I Arnold Chiari Malformation with Syringomyelia and Scoliosis: Radiological Correlations between Tonsillar Descent, Syrinx Morphology and Curve Characteristics: A Retrospective Study

Shanmugasundaram S, Viswanathan VK, Shetty AP, Rai N, Hajare S, Kanna RM, Rajasekaran S

Study Design: Retrospective cohort. Purpose: The current study was planned to evaluate deformity characteristics, assess relationship between morphology of syrinx/Arnold Chiari malformation (ACM) and deformity, analyze effect of posterior fossa decompression...
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Proteomic Signatures of Healthy Intervertebral Discs From Organ Donors: A Comparison With Previous Studies on Discs From Scoliosis, Animals, and Trauma

Rajasekaran S, Tangavel C, Soundararajan DCR, Nayagam SM, Matchado MS, Muthurajan R, Anand KSV, Rajendran S, Shetty AP, Kanna RM, Kuppamuthu D

Objective: To catalog and characterize the proteome of normal human intervertebral disc (IVD). Methods: Nine magnetic resonance imaging (MRI) normal IVDs were harvested from 9 different brain dead yet alive voluntary...
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