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Novel biological strategies to enhance the radiation therapeutic ratio

Kim JH, Jenrow KA, Brown SL

Successful anticancer strategies require a differential response between tumor and normal tissue (i.e., a therapeutic ratio). In fact, improving the effectiveness of a cancer therapeutic is of no clinical value...
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Physical and Biological Background of Radiosurgery

Suh TS, Kim IH

  • KMID: 2340896
  • J Korean Med Assoc.
  • 2008 Jan;51(1):16-26.
Radiosurgery is a highly precise form of radiation therapy for the treatment of vascular lesions, certain primary or metastatic neoplasms, or functional disorders. Either intracranial or extracranial, which are inaccessible...
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Introduction to Radiosurgery

Chung HT, Kim DG

  • KMID: 2340895
  • J Korean Med Assoc.
  • 2008 Jan;51(1):5-15.
Radiosurgery, or stereotactic radiosurgery, is a minimally invasive modality to treat a lesion with stereotactically focused ionizing radiation without surgical incision. Because there are no incision procedures, general anesthesia or...
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CyberKnife(TM) for the Treatment of Non-Metastatic Prostate Cancer

Lee SJ, Song K, Park JW, Gil MC, Jo MK

PURPOSE: The radiobiology of prostate cancer favors a hypofractionated dose regimen. We report here our experience with the CyberKnife(TM), demonstrating its efficacy, safety, and feasibility as a treatment modality for...
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Radiobiological mechanisms of stereotactic body radiation therapy and stereotactic radiation surgery

Kim MS, Kim W, Park IH, Kim HJ, Lee E, Jung JH, Cho LC, Song CW

Despite the increasing use of stereotactic body radiation therapy (SBRT) and stereotactic radiation surgery (SRS) in recent years, the biological base of these high-dose hypo-fractionated radiotherapy modalities has been elusive....
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Alteration of Oleate-Phospholipase D Activities in Some Cell Lines after Irradiation

Kim CY, Choi MU, Choi MS

  • KMID: 2006786
  • J Korean Cancer Assoc.
  • 1997 Dec;29(6):944-953.
PURPOSE: Phospholipase D (PLD) catalyzes the hydrolytic cleavage of terminal phosphate diester bond of glycerophopholipids to produce phosphatidic acid (PA). PLD plays an important role in signal transduction and is...
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Molecular Aspects of Radiotherapy

Park HJ

  • KMID: 2200190
  • J Lung Cancer.
  • 2003 Mar;2(1):10-15.
When tumor cells are exposed to ionizing radiation, various and complicated molecular biological changes take place leading to cell death, mutation, and recovery from sublethal damage. It has been known...
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Multidisciplinary Management of the Locally Advanced Unresectable Non-Small Cell Lung Cancer

Cho KH

  • KMID: 2198615
  • J Korean Soc Ther Radiol Oncol.
  • 2004 Mar;22(1):1-10.
Locally advanced (Stage III) non-small cell lung cancer (NSCLC) accounts for approximately one third of all cases of NSCLC. Few patients with locally advanced NSCLC present with disease amenable to...
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Establishment and Characterization of a Small Cell Lung Cancer Cell Line(JePa-1)

Lee MJ, Jeon HJ, Chung JH

  • KMID: 2275738
  • Korean J Pathol.
  • 1997 Aug;31(8):695-710.
Lung cancer is the most common malignant tumor worldwide and its incidence continues to rise each year. Recent development of molecular biologic method has led to advances in determining the...
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