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Radiobiological mechanisms of stereotactic body radiation therapy and stereotactic radiation surgery

Kim MS, Kim W, Park IH, Kim HJ, Lee E, Jung JH, Cho LC, Song CW

Despite the increasing use of stereotactic body radiation therapy (SBRT) and stereotactic radiation surgery (SRS) in recent years, the biological base of these high-dose hypo-fractionated radiotherapy modalities has been elusive....
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Definitive radiotherapy with or without chemotherapy for clinical stage T4N0-1 non-small cell lung cancer

Kim YJ, Song SY, Jeong SY, Kim SW, Lee JS, Kim SS, Choi W, Choi EK

PURPOSE: To determine failure patterns and survival outcomes of T4N0-1 non-small cell lung cancer (NSCLC) treated with definitive radiotherapy. MATERIALS AND METHODS: Ninety-five patients with T4N0-1 NSCLC who received definitive radiotherapy...
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Neck muscle atrophy and soft-tissue fibrosis after neck dissection and postoperative radiotherapy for oral cancer

Kim J, Shin ES, Kim JE, Yoon SP, Kim YS

Late complications of head and neck cancer survivors include neck muscle atrophy and soft-tissue fibrosis. We present an autopsy case of neck muscle atrophy and soft-tissue fibrosis (sternocleidomastoid, omohyoid, digastric,...
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Prognostic factors in breast cancer with extracranial oligometastases and the appropriate role of radiation therapy

Yoo GS, Yu JI, Park W, Huh SJ, Choi DH

PURPOSE: To identify prognostic factors for disease progression and survival of patients with extracranial oligometastatic breast cancer (EOMBC), and to investigate the role of radiation therapy (RT) for metastatic lesions. MATERIALS...
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The first private-hospital based proton therapy center in Korea; status of the Proton Therapy Center at Samsung Medical Center

Chung K, Han Y, Kim J, Ahn SH, Ju SG, Jung SH, Chung Y, Cho S, Jo K, Shin EH, Hong CS, Shin JS, Park S, Kim DH, Kim HY, Lee B, Shibagaki , Nonaka H, Sasai K, Koyabu Y, Choi C, Huh SJ, Ahn YC, Pyo HR, Lim DH, Park HC, Park W, Oh DR, Noh JM, Yu JI, Song S, Lee JE, Lee B, Choi DH

PURPOSE: The purpose of this report is to describe the proton therapy system at Samsung Medical Center (SMC-PTS) including the proton beam generator, irradiation system, patient positioning system, patient position...
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Radiotherapy as an effective treatment modality for follicular lymphoma: a single institution experience

Choi SH, Cho J, Kim JS, Cheong JW, Suh CO

PURPOSE: Follicular lymphoma (FL) is an indolent non-Hodgkin's lymphoma that is highly sensitive to radiotherapy (RT). However, the effectiveness of RT has not been well established. We reviewed our experiences...
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Feasibility and response of helical tomotherapy in patients with metastatic colorectal cancer

Bae SH, Moon SK, Kim YH, Cho KH, Shin EJ, Lee MS, Ryu CB, Ko BM, Yun J

PURPOSE: To investigate the treatment outcome and the toxicity of helical tomotherapy (HT) in patients with metastatic colorectal cancer (mCRC). MATERIALS AND METHODS: We retrospectively reviewed 18 patients with 31 lesions...
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Treatment outcome of hepatic re-irradiation in patients with hepatocellular carcinoma

Seol SW, Yu JI, Park HC, Lim DH, Oh D, Noh JM, Cho WK, Paik SW

PURPOSE: We evaluated the efficacy and toxicity of repeated high dose 3-dimensional conformal radiation therapy (3D-CRT) for patients with unresectable hepatocellular carcinoma. MATERIALS AND METHODS: Between 1998 and 2011, 45 patients...
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Concurrent chemoradiotherapy improves survival outcome in muscle-invasive bladder cancer

Byun SJ, Kim JH, Oh YK, Kim BH

PURPOSE: To evaluate survival rates and prognostic factors related to treatment outcomes after bladder preserving therapy including transurethral resection of bladder tumor, radiotherapy (RT) with or without concurrent chemotherapy in...
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Met inactivation by S-allylcysteine suppresses the migration and invasion of nasopharyngeal cancer cells induced by hepatocyte growth factor

Cho O, Hwang HS, Lee BS, Oh YT, Kim CH, Chun M

PURPOSE: Past studies have reported that S-allylcysteine (SAC) inhibits the migration and invasion of cancer cells through the restoration of E-cadherin, the reduction of matrix metalloproteinase (MMP) and Slug protein...
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