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Human Monoclonal Antibody Inhibiting Reverse Transcriptase Activity of Hepatitis B Virus Polymerase Protein

Park SJ, Seol SY, Jee SR, Park ET, Lee YJ, Lee SH, Chung JM, Cho HD, Jeong YJ, Choi IH, Park SG

  • KMID: 935184
  • Korean J Gastroenterol.
  • 2007 Feb;49(2):85-92.
BACKGROUND/AIMS: To develop a novel treatment method for hepatitis B virus (HBV) infection, we aimed to make a human monoclonal antibody inhibiting reverse transcriptase (RT) activity of P protein which...
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Genotypic resistance to entecavir in chronic hepatitis B patients

Kim BU, Goo JC, Park BC, Kim SO, Hong SP, Jeong JI, Chae HB, Park SM, Youn SJ

BACKGROUND/AIMS: The prevalence and clinical characteristics of entecavir (ETV) resistance is not well known. The aim of this study was to determine the frequency of genotypic resistance in nonresponders and...
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Long-term clevudine therapy in nucleos(t)ide-naive and lamivudine-experienced patients with hepatitis B virus-related chronic liver diseases

Lee HJ, Eun JR, Lee CH, Hwang JS, Suh JI, Kim BS, Jang BK

BACKGROUNDS/AIMS: Clevudine is an effective antiviral nucleoside analogue, but there are few data regarding its long-term effects, resistance, and safety. The aim of this study was to evaluate the long-term...
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