- A novel beta-glucan produced by Paenibacillus polymyxa JB115 induces nitric oxide production in RAW264.7 macrophages
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Chang ZQ, Lee JS, Hwang MH, Hong JH, Jung HK, Lee SP, Park SC
- KMID: 1102975
- J Vet Sci.
- 2009 Jun;10(2):165-167.
- doi: 10.4142/jvs.2009.10.2.165
The effect of extracellular beta-(1-->3), (1-->6)-glucan, produced by Paenibacillus polymyxa JB115, on nitric oxide (NO) production in RAW264.7 macrophages was investigated. beta-glucan induced the production of NO by RAW264.7 macrophages... -
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- Increased Expression of Glucocorticoid Receptor beta Messenger RNA in Patients with Ankylosing Spondylitis
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Lee CK, Lee EY, Cho YS, Moon KA, Yoo B, Moon HB
- KMID: 1718037
- Korean J Intern Med.
- 2005 Jun;20(2):146-151.
- doi: 10.3904/kjim.2005.20.2.146
BACKGROUND: Glucocorticoids have been known to be less effective for treating ankylosing spondylitis (AS) patients than for treating rheumatoid arthritis (RA) patients. To elucidate the mechanisms underlying this phenomenon, we... -
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- Inhibition of trichostatin A-induced antiangiogenesis by small-interfering RNA for thrombospondin-1
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Kang JH, Kim SA, Chang SY, Hong S, Hong KJ
- KMID: 1047092
- Exp Mol Med.
- 2007 Jun;39(3):402-411.
Expression of thrombospondin-1 (TSP-1), which is a known inhibitor of tumor growth and angiogenesis, is reciprocally regulated by positive regulators, such as VEGF. Additionally, trichostatin A (TSA) suppresses tumor progression... -
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- Changes of splenocyte IFN-gamma mRNA synthesis in rats infected with Paragonimus westermani
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Cho JK, Kwon HS, Joo KH, Lee JS, Cho SW
- KMID: 1715257
- Korean J Parasitol.
- 1999 Dec;37(4):285-287.
- doi: 10.3347/kjp.1999.37.4.285
Changes in the expression level of splenocyte IFN-gamma mRNA of Sprague-Dawley (SD) rats infected with Paragonimus westermani were analyzed by competitive reverse transcription-polymerase chain reaction (RT-PCR) followed by southern... -
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- Expression of urokinase: type plasminogen activator, its receptor, and its inhibitor in gastric adenocarcinoma tissues
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Hong SI, Park IC, Son YS, Lee SH, Kim BG, Lee JI, Lee TW, Kook YH, Min YI, Hong WS
- KMID: 932128
- J Korean Med Sci.
- 1996 Feb;11(1):33-37.
- doi: 10.3346/jkms.1996.11.1.33
The plasminogen and plasmin system, which is mainly regulated by urokinase-type plasminogen activator (uPA), its receptor (uPAR) and its inhibitor (PAI-1), is generally believed to play a role in cancer... -
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- Expression of HuD (a paraneoplastic encephalomyelitis antigen) mRNA in lung cancer
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Cho JH, Noguchi M
- KMID: 1081051
- J Korean Med Sci.
- 1997 Aug;12(4):305-310.
- doi: 10.3346/jkms.1997.12.4.305
HuD, one of the Hu antigens (HuD and HuC), was recognized in the sera of small cell lung cancer (SCLC) patients with antibody-associated paraneoplastic encephalomyelitis/peripheral sensory neuropathy (PEM/PSN). Three... -
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- Overexpression of tissue inhibitors of metalloproteinase-1 and -2 in the stroma of gastric cancer
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Hong SI, Park IC, Hong WS, Son YS, Lee SH, Lee JI, Choi DW, Moon NM, Choe TB, Jang JJ
- KMID: 645010
- J Korean Med Sci.
- 1996 Dec;11(6):474-479.
- doi: 10.3346/jkms.1996.11.6.474
The fundamental event of cancer invasion and metastasis is the complicated interaction of cancer cells with host cells, in which event, a number of proteases and their inhibitors are involved.... -
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- Eupatilin Ameliorates Collagen Induced Arthritis
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Kim J, Kim Y, Yi H, Jung H, Rim YA, Park N, Jung SM, Park SH, Ju JH
- KMID: 2133298
- J Korean Med Sci.
- 2015 Mar;30(3):233-239.
- doi: 10.3346/jkms.2015.30.3.233
Eupatilin is the main active component of DA-9601, an extract from Artemisia. Recently, eupatilin was reported to have anti-inflammatory properties. We investigated the anti-arthritic effect of eupatilin in a murine... -
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- Decreased nitric oxide synthesis in rats with chronic renal failure
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Kim SW, Lee JU, Paek YW, Kang DG, Choi KC
- KMID: 1730639
- J Korean Med Sci.
- 2000 Aug;15(4):425-430.
- doi: 10.3346/jkms.2000.15.4.425
The present study was aimed at investigating whether an altered role of nitric oxide (NO) is involved in chronic renal failure (CRF). Rats were subjected to 5/6 nephrectomy and kept... -
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- Transcriptional and translational expression of calbindin-D9k in the duodenum, kidney and uterus of a female canine model
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Sim JY, Jung EM, Yoo YM, Choi KC, Jeung EB
- KMID: 1106152
- J Vet Sci.
- 2010 Mar;11(1):15-19.
- doi: 10.4142/jvs.2010.11.1.15
Calbindin-D9k (CaBP-9k) is a cytosolic calcium-binding protein expressed in tissues in the intestine, uterus, placenta, kidney, pituitary gland and bone. Its exact function is unknown, but it is considered to... -
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- In vitro Model System of Transepithelial Migration of Neutrophil by Helicobacter pylori
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Jung HC, Kim JG, Kim JM, Song IS, Park SM
- KMID: 772517
- Korean J Gastroenterol.
- 2003 Jul;42(1):20-26.
BACKGROUND/AIMS: Migration of neutrophil across the intestinal epithelium is a structural hallmark of active intestinal diseases. One of the characteristic histologic features of Helicobacter pylori (H. pylori) infection is... -
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- Cathepsin L derived from skeletal muscle cells transfected with bFGF promotes endothelial cell migration
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Chung JH, Im EK, Jin T, Lee SM, Kim SH, Choi EY, Shin MJ, Lee KH, Jang Y
- KMID: 1104387
- Exp Mol Med.
- 2011 Apr;43(4):179-188.
- doi: 10.3858/emm.2011.43.4.022
Gene transfer of basic fibroblast growth factor (bFGF) has been shown to induce significant endothelial migration and angiogenesis in ischemic disease models. Here, we investigate what factors are secreted from... -
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- Estradiol regulates miR-135b and mismatch repair gene expressions via estrogen receptor-beta in colorectal cells
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He YQ, Sheng JQ, Ling XL, Fu L, Jin P, Yen L, Rao J
- KMID: 1402316
- Exp Mol Med.
- 2012 Dec;44(12):723-732.
Estrogen has anti-colorectal cancer effects which are thought to be mediated by mismatch repair gene (MMR) activity. Estrogen receptor (ER) expression is associated with microRNA (miRNA) expression in ER-positive tumors.... -
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- Genes Associated with Recurrence of Hepatocellular Carcinoma: Integrated Analysis by Gene Expression and Methylation Profiling
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Yang JD, Seol SY, Leem SH, Kim YH, Sun Z, Lee JS, Thorgeirsson SS, Chu IS, Roberts LR, Kang KJ
- KMID: 1123442
- J Korean Med Sci.
- 2011 Nov;26(11):1428-1438.
- doi: 10.3346/jkms.2011.26.11.1428
Gene expression is suppressed by DNA methylation. The goal of this study was to identify genes whose CpG site methylation and mRNA expression are associated with recurrence after surgical resection... -
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