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Inhibition of phospholipase D2 induces autophagy in colorectal cancer cells

Hwang WC, Kim MK, Song JH, Choi KY, Min DS

Autophagy is a conserved lysosomal self-digestion process used for the breakdown of long-lived proteins and damaged organelles, and it is associated with a number of pathological processes, including cancer. Phospholipase...
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Effects of Interleukin-13 and Montelukast on the Expression of Zonula Occludens-1 in Human Podocytes

Park SJ, Saleem MA, Nam JA, Ha TS, Shin JI

PURPOSE: The aim of this study was to investigate whether pathologic changes in zonula occludens-1 (ZO-1) are induced by interleukin-13 (IL-13) in the experimental minimal-change nephrotic syndrome (MCNS) model and...
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