- Gefitinib-induced Acute Fatal Respiratory Failure in a Woman who Never Smoked and had Adenocarinoma of the Lung with EGFR Mutation
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Kim SG, Ryu JS, Han JY, Kim HJ, Cho JH, Kwak SM, Lee HL
- KMID: 1478141
- Tuberc Respir Dis.
- 2008 Jan;64(1):44-47.
- doi: 10.4046/trd.2008.64.1.44
No abstract available. -
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- Drug-Induced Dilated Cardiomyopathy Associated with Anagrelide
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Kim SY, Kim JY, Youn YJ, Lee NS, Ahn MS, Lee KH, Kim HY, Choe KH
- KMID: 1486393
- J Cardiovasc Ultrasound.
- 2008 Dec;16(4):130-132.
- doi: 10.4250/jcu.2008.16.4.130
Anagrelide is an effective drug for essential thrombocythaemia, and its adverse cardiovascular effects are relatively rarely reported. We experienced a 73 year-old man with essential thrombocythaemia developed anagrelide-induced dilated cardiomyopathy.... -
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- A Case of Fatal Fenazaquin Intoxication Showing Severe Lactic Acidosis
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Lee BK, Jeung KW, Ryu HH, Heo T, Min YI, Lee HY
- KMID: 2332799
- J Korean Soc Emerg Med.
- 2010 Aug;21(4):520-523.
Fenazaquin (4-[[4 (1,1-dimethylethyl) pheynyl]ethoxy]quinazoline) is an insecticide that inhibits NADH ubiquinone oxidoreductase of the mitochondria, which is also known as complex I. An 83 year old female was brought to... -
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- Successful Rechallenge with Gefitinib for an Initial Erlotinib-Responder with Advanced Lung Adenocarcinoma
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Hong SC, Sim YS, Lee JH, Ryu YJ, Chang JH
- KMID: 2319566
- Tuberc Respir Dis.
- 2011 Oct;71(4):286-290.
Although failure of epidermal growth factor receptor tyrosine kinase inhibitors (EGFR TKI) is generally believed to be associated with cross-resistance to other EGFR TKI, the benefit of administering erlotinib as... -
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- The Effectiveness of Gefitinib on Spinal Metastases of Lung Cancer: Report of Two Cases
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Zukawa M, Nakano M, Hirano N, Mizuhashi , Kanamori M
- KMID: 1972537
- Asian Spine J.
- 2008 Dec;2(2):109-113.
- doi: 10.4184/asj.2008.2.2.109
Lung cancer has a high mortality rate and is often diagnosed at the metastatic stage. Recently, gefitinib, a molecule target therapeutic drug, has offered a new approach for patients with... -
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- Comparison of DPP-4 Inhibitors
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Kim NH, Kim SG
- KMID: 2173918
- J Korean Diabetes.
- 2013 Sep;14(3):111-119.
- doi: 10.4093/jkd.2013.14.3.111
During past several years, a novel class of antihyperglycemic agents, dipeptidyl peptidase-4 (DPP-4) inhibitors, has become one of the most important options in the management of type 2 diabetes. These... -
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- Erlotinib HCL (Tarceva(R)) Induced Radiation Recall Dermatitis
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Kim HM, Lee SH, Kim CY
- KMID: 2247677
- Korean J Dermatol.
- 2010 Oct;48(10):872-875.
Erlotinib (Tarceva(R)) is a new anti-cancer agent that acts by inhibiting epidermal growth factor receptor (EGFR) signal transduction. It is currently used in the treatment of advanced stage non-small cell... -
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- A case of leptomeningeal metastasis from adenocarcinoma of the lung improved by treatment with Gefitinib
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Yu SK, Park WJ, Park CS, Chin HJ, Shin KC, Chung JH, Lee KH
- KMID: 2256264
- Korean J Med.
- 2008 Feb;74(2):198-202.
Leptomeningeal metastasis occurs in approximately 1% of patients with non-small cell lung cancer and this is an extremely serious complication. Without treatment, the median survival of patients is 4~6 weeks.... -
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- Personalized therapy for advanced breast cancer using molecular signatures
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Jung KH
- KMID: 2305798
- Korean J Med.
- 2009 Jul;77(1):26-34.
In Korea, breast cancer is the second common cancer in women and many patients suffer from metastatic disease after surgery and adjuvant therapy. Metastatic breast cancer is unlikely to be... -
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- Erlotinib (Tarceva(R)) Induced Hair Abnormalities
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Choi CM, Lew BL, Sim WY
- KMID: 2247599
- Korean J Dermatol.
- 2011 Apr;49(4):382-384.
Erlotinib is a low-molecular-weight quinazoline derivative that inhibits the activation of epidermal growth factor receptor (EGFR) tyrosine kinase through competitive binding of the adenosine triphosphate binding domain of the receptor.... -
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- Two Cases of Acneiform Eruption Caused by Epidermal Growth Factor Receptor Inhibitors
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Choi KW, Lee CY, Lee YK, Kim HS, Kim KH, Kim YH
- KMID: 2248163
- Korean J Dermatol.
- 2008 Jun;46(6):862-865.
Epidermal growth factor receptor (EGFR) inhibitors are associated with unique and dramatical dermatological side effects. The most commonly encountered adverse effect is a mild skin toxicity characterized by a sterile... -
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- Black Hairy Tongue Associated with Erlotinib Treatment in a Patient with Advanced Lung Cancer
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Jeong JS, Lee JY, Kim MK, Yoon TY
- KMID: 2383260
- Ann Dermatol.
- 2011 Nov;23(4):526-528.
Erlotinib is a tyrosine kinase inhibitor that acts on the epidermal growth factor receptor (EGFR). There have been many reports of the mucocutaneous side effects related to several EGFR inhibitors... -
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- Patient Compliance and Associated Factors for Treatment with Alfuzosin XL 10mg (UroXatral(R))
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Jung TS, Kim YD, Lee MH, Yang WJ, Song YS, Park YH
- KMID: 2226553
- Korean J Androl.
- 2008 Dec;26(4):223-226.
PURPOSE: Alfuzosin XL (Sanofi-Aventis, UroXatral(R)) has to be taken just after a meal for the best efficacy due to its specific pharmacokinetics. We studied patient compliance and associated factors with... -
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- A Case of Cicatricial Alopecia Associated with Erlotinib
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Yang BH, Bang CY, Byun JW, Han SH, Song HJ, In SG, Shin JH, Choi GS
- KMID: 2171870
- Ann Dermatol.
- 2011 Dec;23(Suppl 3):S350-S353.
- doi: 10.5021/ad.2011.23.S3.S350
Erlotinib is a small-molecule tyrosine kinase inhibitor (TKI) of the epidermal growth factor receptor (EGFR). Erlotinib has been used primarily to treat non-small cell lung cancer. In addition to its... -
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- Gefitinib Treatment for Pulmonary Sarcomatoid Carcinoma Driven by an EGFR Mutation: Two Cases
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Kim JY, Lim Y, Lee E, Kim MS, Lee DW, Kim TM, Lee SH
- KMID: 1833860
- Korean J Med.
- 2013 Mar;84(3):446-451.
- doi: 10.3904/kjm.2013.84.3.446
Sarcomatoid carcinoma of the lung is defined as a group of poorly differentiated non-small cell carcinomas that contain a component of sarcoma or a sarcoma-like element. Most sarcomatoid carcinomas are... -
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- Gefitinib Inhibits the Growth of Toxoplasma gondii in HeLa Cells
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Yang Z, Ahn HJ, Nam HW
- KMID: 1792207
- Korean J Parasitol.
- 2014 Aug;52(4):439-441.
- doi: 10.3347/kjp.2014.52.4.439
Toxoplasma gondii is the causative agent of toxoplasmosis with symptoms of congenital neurological and ocular diseases and acquired lymphadenitis, retinochoroiditis, and meningoencephalitis. Small molecules which block the activity of protein... -
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- A Case of Residual Non-Small Cell Lung Cancer Cells Coexisting With Newly Developed Small Cell Lung Cancer Cells in Ascitic Fluid after Chemotherapy for Non-Small Cell Lung Cancer
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Park SH, Chi HS, Kim YJ, Cho YU, Jang S, Park CJ, Kim SW
- KMID: 1791913
- Ann Lab Med.
- 2014 Mar;34(2):163-165.
- doi: 10.3343/alm.2014.34.2.163
No abstract available. -
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- Leukocytoclastic Vasulitis Induced by Gefitinib
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Hong JW, Jeon SY, Lee KY, Song KH, Kim KH, Kim YH
- KMID: 2146310
- Korean J Dermatol.
- 2011 Jan;49(1):50-52.
Gefitinib (Iressa(R), AstraZeneca) is an oral form of an anticancer drug called epidermal growth factor receptor-tyrosine kinase inhibitor. It is widely used for various solid cancers, including lung cancer. Cutaneous... -
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- Stevens-Johnson Syndrome Induced by Vandetanib
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Yoon J, Oh CW, Kim CY
- KMID: 2171868
- Ann Dermatol.
- 2011 Dec;23(Suppl 3):S343-S345.
- doi: 10.5021/ad.2011.23.S3.S343
Vandetanib is a once-daily oral anticancer drug that selectively inhibits key signaling pathways in cancer by targeting vascular endothelial growth factor receptors, epidermal growth factor receptors tyrosine kinase, and rearranged... -
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- Comparison of Gefitinib versus Docetaxel in Patients with Pre-Treated Non-Small Cell Lung Cancer (NSCLC)
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Hirsh V
- KMID: 2199965
- J Lung Cancer.
- 2009 Dec;8(2):61-66.
- doi: 10.6058/jlc.2009.8.2.61
More effective treatments in first, second, and third-line of metastatic non-small cell lung cancer (NSCLC) enable patients to live longer, with a better quality of life (QOL). Especially epidermal growth... -
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