- Suppression of multidrug resistance via inhibition of heat shock factor by quercetin in MDR cells
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Kim SH, Yeo GS, Lim YS, Kang CD, Kim CM, Chung BS
- KMID: 754993
- Exp Mol Med.
- 1998 Jun;30(2):87-92.
MDR1 promoter has been shown to contain heat shock elements (HSE), and it has been reported that FM3A/M and P388/M MDR cells show a constitutively activated heat shock factor (HSF), suggesting that... -
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- Expression of Heat Shock Protein 70 Modulates the Chemoresponsiveness of Pancreatic Cancer
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Hyun JJ, Lee HS, Keum B, Seo YS, Jeen YT, Chun HJ, Um SH, Kim CD
- KMID: 1712336
- Gut Liver.
- 2013 Nov;7(6):739-746.
BACKGROUND/AIMS: Heat shock protein (HSP) 70 is constitutively overexpressed in pancreatic cancer cells (PCCs) and appears to confer protection against chemotherapeutics. We investigated whether modulating HSP 70 increases chemoresponsiveness to... -
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- Antiproliferation and Redifferentiation in Thyroid Cancer Cell Lines by Polyphenol Phytochemicals
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Kang HJ, Youn YK, Hong MK, Kim LS
- KMID: 1094260
- J Korean Med Sci.
- 2011 Jul;26(7):893-899.
- doi: 10.3346/jkms.2011.26.7.893
Thyroid carcinogenesis is accompanied by loss of thyroid-specific functions and refractory to radioiodine and thyroid stimulating hormone (TSH) suppression therapy. Redifferentiating agents have been shown to inhibit tumor growth and... -
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