- The Impact of Inosine Triphosphatase Variants on Hemoglobin Level and Sustained Virologic Response of Chronic Hepatitis C in Korean
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Kim JS, Ahn SM, Jung YK, Kwon OS, Kim YS, Choi DJ, Kim JH
- KMID: 1793028
- J Korean Med Sci.
- 2013 Aug;28(8):1213-1219.
- doi: 10.3346/jkms.2013.28.8.1213
Two variants of the inosine triphosphatase (ITPA: rs1127354, rs7270101) gene cause ITPA deficiency and protect against the hemolytic toxicity of ribavirin. We investigated the clinical significance of ITPA variants in... -
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- Impact of ENPP1 K121Q on Change of Insulin Resistance after Web-Based Intervention in Korean Men with Diabetes and Impaired Fasting Glucose
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Kang JY, Sung SH, Lee YJ, Choi TI, Choi SJ
- KMID: 2129624
- J Korean Med Sci.
- 2014 Oct;29(10):1353-1359.
- doi: 10.3346/jkms.2014.29.10.1353
Ectoenzyme nucleotide pyrophosphate phosphodiesterase 1 (ENPP1) gene has been studied in relation to type 2 diabetes mellitus (T2DM) and insulin resistance (IR). We hypothesized that the difference in genotype may... -
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- Association between IPTA Gene Polymorphisms and Hematological Abnormalities in Hepatitis C Virus-Infected Patients Receiving Combination Therapy
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Hwang JJ, Lo CC, Lin CH, Cheng HS, Hung IW, Tsai WJ, Hung CH
- KMID: 2380767
- Gut Liver.
- 2015 Mar;9(2):214-223.
- doi: 10.5009/gnl14095
BACKGROUND/AIMS: Hematological abnormalities during hepatitis C virus (HCV) combination therapy with pegylated interferon alpha and ribavirin often necessitate dose reduction. Variants of the ITPA gene have been reported to protect... -
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- The K121Q Polymorphism in ENPP1 (PC-1) Is Not Associated with Type 2 Diabetes or Obesity in Korean Male Workers
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Seo HJ, Kim SG, Kwon OJ
- KMID: 1786885
- J Korean Med Sci.
- 2008 Jun;23(3):459-464.
- doi: 10.3346/jkms.2008.23.3.459
Type 2 diabetes is characterized by insulin resistance, and ENPP1 plays an important role in insulin resistance. We investigated the association of the ENPP1 K121Q polymorphism with both diabetes and... -
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