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Involvement of a Novel Organic Cation Transporter in Paeonol Transport Across the Blood-Brain Barrier

Gyawali A, Krol S, Kang YS

Paeonol has neuroprotective function, which could be useful for improving central nervous system disorder. The purpose of this study was to characterize the functional mechanism involved in brain transport of...
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Imperatorin is Transported through Blood-Brain Barrier by Carrier-Mediated Transporters

Tun T, Kang YS

Imperatorin, a major bioactive furanocoumarin with multifunctions, can be used for treating neurodegenerative diseases. In this study, we investigated the characteristics of imperatorin transport in the brain. Experiments of the...
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The study for the roles of intratracheally administered histamine in the neutrophil-mediated acute lung injury in rats:

Koh Y, Hybertson , Jepson EK, Kim MJ, Lee IC, Lim CM, Lee SD, Kim WS, Kim DS, Kim WD, Repine JE

BACKGROUND: Neutrophils are considered to play critical roles in the development of acute respiratory distress syndrome. Histamine, which is distributed abundantly in lung tissue, increases the rolling of neutrophills via...
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