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Actions of potassium channel openers in rat detrusor urinae

Kim SJ, Kim NS, Lee JL

This study was performed to investigate the action of potassium channel openers on the mechanical activity of detrusor muscle isolated from rats. Detrusor muscle strips, 15 mm in length, were...
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Salinomycin reduces stemness and induces apoptosis on human ovarian cancer stem cell

Lee HG, Shin SJ, Chung HW, Kwon SH, Cha SD, Lee JE, Cho CH

OBJECTIVE: Cancer stem cells (CSCs) represent a subpopulation of undifferentiated tumorigenic cells thought to be responsible for tumor initiation, maintenance, drug resistance, and metastasis. The role of CSCs in drug...
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p53 and DNA-dependent protein kinase catalytic subunit independently function in regulating actin damage-induced tetraploid G1 arrest

Chae HD, Kim SY, Park SE, Kim J, Shin DY

We previously reported that the p53 tumor suppressor protein plays an essential role in the induction of tetraploid G1 arrest in response to perturbation of the actin cytoskeleton, termed actin...
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