- Immunocytochemical and ultrastructural study of localization of the putrescine in rat medulla oblongata
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Lee JE, Park KA, Lee SG, Cho YD
- KMID: 1686747
- Korean J Anat.
- 1991 Dec;24(4):409-421.
No abstract available. -
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- Effect of Melatonin Administration on the Immobilization Stress-induced Polyamine Responses in Brain and Gastrointestinal Tract
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Kang YW, Lee SR
- KMID: 2286949
- Korean J Psychopharmacol.
- 2000 Jun;11(2):160-167.
OBJECTIVE: The present study was designed to identify the acute and chronic immobilization stress-induced polyamine (putrescine) responses and their modulation by administration of melatonin in brain regions (frontal cortex and hippocampus) and... -
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- Association of dexamethasone-induced apoptosis of G|1-arrest of human leukemic CEM cells with polyamine deficit
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Choi SH, Lee JA, Chae YS, Min BH, Chun YS, Chun BG
- KMID: 2071517
- Korean J Physiol Pharmacol.
- 1997 Aug;1(4):457-466.
The effects of DFMO or/and putrescine on the dexamethasone-induced apoptosis of CEM cells were studied to investigate the role of polyamines in anti-leukemic glucocorticoid action. Dexamethasone-induced apoptosis was preceded by significant decreases of cellular... -
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- Relaxation Responses of Isolated Rabbit Seminal Vesicle to Polyamines
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Myung SC, Lee SY, Kang GH, Keum EM, Lee MY, Kim SC
- KMID: 2293954
- Korean J Urol.
- 2005 Feb;46(2):169-173.
PURPOSE: This study was designed to investigate the effects of polyamines on rabbit seminal vesicular contractility. MATERIALS AND METHODS: The polyamines; putrescine, spermidine and spermine, were added to deepithelized and precontracted... -
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- Effect of lithium on the Polyamine Response in Brain after Stress
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Lee SR
- KMID: 2286968
- Korean J Psychopharmacol.
- 1998 Apr;9(1):35-41.
OBJECTIVE: The present study was designed to identify the stress-induced polyamine (PA) response and its modulation by chronic treatment of lithium in brain (hippocampus) and periphery (liver). METHOD: For immobilization... -
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- Involvement of Polyamine in Growth Hormine Secretion from the GH3 Cells
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Lee JY, Kim BK
- KMID: 2331104
- J Korean Soc Endocrinol.
- 1998 Sep;13(3):313-323.
BACKGROUNDS: Polyamines are known to be essential for cell growth and differentiation. Recently, possible roles of the polyamine in signal transduction as neurotransmitter, modulator, or second messenger are suggested in... -
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- Effects of dexamethasone and DHEA on the changes of glutamate and polyamine uptake in rat astrocytes by lipopolysaccharide and antimycin A
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Choi SH, Lee B, Shin KH, Min BH, Chun YS, Chun BG
- KMID: 1554128
- Korean J Physiol Pharmacol.
- 1999 Apr;3(2):137-146.
Interactions among dexamethasone, dehydroepiandrosterone (DHEA), lipopolysaccharide (LPS), and antimycin A on the glutamate uptake and the polyamine uptake were investigated in primary cultures of rat cerebral cortical astrocytes to examine the effects of... -
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- The Effect of Delayed Administration of Green Tea Polyphenol, (-)-pigallocatechin-3-gallate, on the Change of Putrescine Level and Hippocampal Neuronal Cell Damage after Transient Global Ischemia in Gerbil
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Lee SR, Kim SP, Yim MB
- KMID: 2010306
- J Korean Neurosurg Soc.
- 2003 Jan;33(1):67-72.
OBJECTIVE: T(-)-Epigallocatechin gallate(EGCG) `a green tea polyphenol' is a potent antioxidant and known to reduce the free radical-induced lipid peroxidation. In our previous study, systemic administration of EGCG immediately after... -
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- Effect of Melatonin on Brain Polyamine Contents and Hippocampal Neuronal Damage after Transient Global Ischemia in Mongolian Gerbil
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Jang YS, Kim DH, Suh YS, Yim MB, Lee SR
- KMID: 1932162
- Korean J Cerebrovasc Dis.
- 2002 Mar;4(1):46-51.
OBJECTIVES: This study was designed to examine whether melatonin has a neuroprotective effect against hippocampal neuronal damage following transient global ischemia in a gerbil. Polyamine is known to play a... -
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- Relaxant Effect of Spermidine on Acethylcholine and High K+-induced Gastric Contractions of Guinea-Pig
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Kim YC, Sim JH, Choi W, Kim CH, You RY, Xu WX, Lee SJ
- KMID: 1486144
- Korean J Physiol Pharmacol.
- 2008 Apr;12(2):59-64.
- doi: 10.4196/kjpp.2008.12.2.59
In our previous study, we found that spermine and putrescine inhibited spontaneous and acetylcholine (ACh)-induced contractions of guinea-pig stomach via inhibition of L-type voltage- dependent calcium current (VDCCL). In this... -
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- Urinary Polyamine Profiles and Benign Prostatic Hyperplasia
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Hong SJ, Chung BH, Seo JW, Chung BC, Park DS, Lee DH
- KMID: 1663287
- Korean J Urol.
- 1996 Dec;37(12):1398-1403.
Polyamines are non-specific marker of cellular proliferation in many malignant tumors, and it is also increase in certain benign conditions. We measured the urinary polyamines to investigate the possibility as... -
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- Effect of Melatonin on the Changes of Hippocampal Polyamine Content and Neuronal Damage Following Transient Global Ischemia in Mongolian Gerbil: a Study of the Differences of Pre- and Post-ischemic Treatment
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Lee SR, Cheun JK
- KMID: 2091626
- Korean J Anesthesiol.
- 2001 May;40(5):664-670.
- doi: 10.4097/kjae.2001.40.5.664
BACKGROUND: We designed this study to examine whether melatonin has a neuroprotective effect against hippocampal neuronal damage following transient global ischemia in a gerbil. Because polyamine is known to participate... -
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- Polyamines and Their Metabolites as Diagnostic Markers of Human Diseases
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Park MH, Igarashi K
- KMID: 2170679
- Biomol Ther.
- 2013 Jan;21(1):1-9.
Polyamines, putrescine, spermidine and spermine, are ubiquitous in living cells and are essential for eukaryotic cell growth. These polycations interact with negatively charged molecules such as DNA, RNA, acidic proteins... -
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