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Adenosine Receptor Agonists Modulate Visceral Hyperalgesia in the Rat

Sohn CI, Park HJ, Gebhart GF

  • KMID: 2009155
  • Gut Liver.
  • 2008 Jun;2(1):39-46.
BACKGROUND/AIMS: Adenosine is an endogenous modulator of nociception. Its role in visceral nociception, particularly in visceral hyperalgesia, has not been studied. The aim of this study was to determine the...
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The Interaction of Morphine and Adenosine Receptor Agonists on Antiallodynia in Rats with a Nerve Ligation Injury

Lee JR, Kim YK, Choi DK, Park JY, Kwak MJ, Hwang JH

BACKGROUND: A Nerve ligation injury may produce a pain syndrome that includes tactile allodynia. Reversal effects on tactile allodynia have been demonstrated after an intrathecal administration of adenosine...
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cAMP-dependent signalling is involved in adenosine-stimulated Cl- secretion in rabbit colon mucosa

Oh SO, Kim EY, Jung JS, Woo JS, Kim YK, Lee SH

  • KMID: 2285215
  • Korean J Physiol Pharmacol.
  • 1998 Aug;2(4):521-527.
An important property of the intestine is the ability to secrete fluid. The intestinal secretion is regulated by a number of substances including vasoactive intestinal peptide (VIP), ATP and different inflammatory mediators. One...
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The interaction of intrathecal neostigmine and N(6)-cyclohexyladenosine on anti-allodynic effects in rats with a nerve ligation injury

Choi DK, Choi SS, Hwang JH

BACKGROUND: Nerve ligation injury in rats produces a pain syndrome that includes mechanical allodynia. Intrathecal administration of cholinesterase inhibitors or adenosine receptor agonists have anti-allodynic effects in this model. Therefore,...
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