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Neosensitization to Multiple Drugs Following Valproate-Induced Drug Reaction with Eosinophilia and Systemic Symptoms Syndrome

Song JM, Jung YE, Park JH, Kim MD, Cheon MS, Lee CI

Drug Reaction with Eosinophilia and Systemic Symptoms (DRESS) syndrome is associated with severe skin eruptions, fever, hematological abnormalities, and multi-organ involvement. Although aromatic anticonvulsant drugs have been frequently associated with...
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Psychometric Properties of the Coping Inventory for Stressful Situations in Korean Adults

Choi Y, Moon E, Park JM, Lee BD, Lee YM, Jeong HJ, Chung YI

OBJECTIVE: The Coping Inventory for Stressful Situations (CISS) is a globally recognized measure of stress coping methods. However, research into the applicability of the CISS in a Korean context is...
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Development of a Biomarker-Based Diagnostic Algorithm for Posttraumatic Syndrome after Physical Injury: Design of the BioPTS Study

Kim JW, Kang HJ, Bae KY, Kim SW, Oh HK, Kim MG, Kim JM

Severe physical injury is a leading cause of posttraumatic syndrome (PTS). This is to develop a biomarker-based diagnostic algorithm for posttraumatic syndrome (BioPTS) study. This is a 2-year longitudinal cohort...
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The Role of Conformity in Relation to Cohesiveness and Intimacy in Day-Hospital Groups of Patients with Schizophrenia

Park IH, Park SY, Choi S, Lee SY, Kim JJ

OBJECTIVE: Conformity is defined as the act of adjusting one's behavior to match the social responses of others. Patients with schizophrenia often adjust their maladaptive behaviors by conforming in group...
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Somatic Symptoms as Mediating Factors between the Perceived Social Support and the Health-Related Quality of Life in North Korean Defectors

Won SD, Lee SH, Kim S, Jun JY, Shin SS

OBJECTIVE: This study was conducted to examine the mediating effect of somatic symptoms between perceived social support and health-related quality of life among North Korean defectors living in South Korea. METHODS:...
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Neuroprotection in Schizophrenia and Its Therapeutic Implications

Kim YK, Na KS

Schizophrenia is a chronic and debilitating mental disorder. The persisting negative and cognitive symptoms that are unresponsive to pharmacotherapy reveal the impairment of neuroprotective aspects of schizophrenia. In this review,...
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Posttraumatic Embitterment Disorder and Hwa-byung in the General Korean Population

Joe S, Lee JS, Kim SY, Won SH, Lim JS, Ha KS

OBJECTIVE: Posttraumatic embitterment disorder (PTED) is characterized by states of “embitterment”, characteristically similar to “Hwa-byung”, which is a Korean culture-bound syndrome. The present study aimed to assess diagnostic relationships between...
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Transdermal Nicotine Patch Effects on EEG Power Spectra and Heart Rate Variability During Sleep of Healthy Male Adults

Choi JB, Lee YJ, Jeong DU

OBJECTIVE: The effect of transdermal nicotine patch on sleep physiology is not well established. The current study aimed to examine the influence of nicotine patch on homeostatic sleep propensity and...
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A Case Report of a 37-Year-Old Alzheimer's Disease Patient with Prominent Striatum Amyloid Retention

Um YH, Choi WH, Jung WS, Park YH, Lee CU, Lim HK

With recent advancement in amyloid imaging, diagnostic application of this new modality has become a great interest among researchers. New ligands, such as 18F- florbetaben, florbetapir and flutemetamol, have been...
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Dementia Care by Healthy Elderly Caregivers Is Associated with Improvement of Patients' Memory and the Caregivers' Quality of Life: A Before and After Study

Kang SG, Na KS, Kang JM, Yeon BK, Lee JY, Cho SJ

OBJECTIVE: The provision of care for elderly people with dementia by healthy elderly caregivers is one of the new health-care paradigms in South Korea. The aim of this study was...
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Validation of the Korean Version of the Clinical Assessment Interview for Negative Symptoms

Jang SK, Park SC, Choi KH, Yi JS, Park JK, Lee JS, Lee SH

OBJECTIVE: Clinical Assessment Interview for Negative Symptoms (CAINS) has recently been developed to improve measurement of negative symptoms in schizophrenia. We performed a multi-center study to validate the Korean version...
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Altered Function of Ventrolateral Prefrontal Cortex in Adolescents with Peer Verbal Abuse History

Lee SW, Choi J, Lee JS, Yoo JH, Kim KW, Kim D, Park H, Jeong B

OBJECTIVE: Previous studies showing the association of exposure to peer (PeVA) and parental verbal abuse in childhood with structural alterations in the young adult brain suggest functional changes in adolescence....
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Effects of Mind-Body Training on Cytokines and Their Interactions with Catecholamines

Jang JH, Park HY, Lee US, Lee KJ, Kang DH

OBJECTIVE: Mind-body training (MBT) may control reactions to stress and regulate the nervous and immune systems. The present study was designed to assess the effects of MBT on plasma cytokines...
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Balance Deficit and Brain Connectivity in Children with Attention-Deficit/Hyperactivity Disorder

Kim SM, Hyun GJ, Jung TW, Son YD, Cho IH, Kee BS, Han DH

OBJECTIVE: We aimed to assess disturbances in postural and gait balance and functional connectivity within the brain regions controlling balance in children with attention-deficit/hyperactivity disorder (ADHD). METHODS: Thirteen children with ADHD...
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Factors Associated with Insomnia among the Elderly in a Korean Rural Community

Kim WJ, Joo WT, Baek J, Sohn SY, Namkoong K, Youm Y, Kim HC, Park YR, Chu SH, Lee E

OBJECTIVE: Sleep disturbance is common in the elderly, which is result from multi-factorial causes encompassing socio-demographic, behavioral, and clinical factors. We aimed to identify factors associated with insomnia among the...
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Microstructural Abnormalities of Basal Ganglia and Thalamus in Bipolar and Unipolar Disorders: A Diffusion Kurtosis and Perfusion Imaging Study

Zhao L, Wang Y, Jia Y, Zhong S, Sun Y, Zhou Z, Zhang Z, Huang L

OBJECTIVE: Bipolar disorder (BD) is often misdiagnosed as unipolar depression (UD), leading to mistreatment and poor clinical outcomes. However, little is known about the similarities and differences in subcorticalgray matter...
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Psychological Factors Influence the Irritable Bowel Syndrome and Their Effect on Quality of Life among Firefighters in South Korea

Jang SH, Ryu HS, Choi SC, Lee SY

OBJECTIVE: The purpose of this study was to investigate the characteristics of psychological factors that are related to irritable bowel syndrome (IBS) and their effects on the quality of life...
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Association of Serotonin 1A Receptor Polymorphism with Variation in Health-Related Quality of Life in Korean Hemodialysis Patients

Park HC, Park S, Choi HY, Lee JE, Park HY, Kim SH, Ha SK, Seok JH

OBJECTIVE: Hemodialysis patients may have psychological distress and reduced quality of life (QoL) related to chronic physical health problems. Genetic polymorphisms associated with reduced QoL in hemodialysis patients. The aim...
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Agoraphobia and Follicle-Stimulating Hormone Levels between Tamoxifen and Goserelin versus Tamoxifen Alone in Premenopausal Hormone Receptor-Positive Breast Cancer: A 12-Month Prospective Randomized Study

Heo JY, Yi H, Fava M, Mischoulon D, Kim K, Yoon S, Jeon HJ, Lee JE

OBJECTIVE: Tamoxifen is an estrogen receptor antagonist used to prevent recurrence of breast cancer, which may provoke depression and anxiety and increase follicle-stimulating hormone (FSH) to patients. We compared anxiety...
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Clinical Dementia Rating Orientation Score as an Excellent Predictor of the Progression to Alzheimer's Disease in Mild Cognitive Impairment

Kim JW, Byun MS, Sohn BK, Yi D, Seo EH, Choe YM, Kim SG, Choi HJ, Lee JH, Chee IS, Woo JI, Lee DY

OBJECTIVE: This study aimed to examine the usefulness of each subscale score of the Clinical Dementia Rating (CDR) for predicting Alzheimer's disease (AD) dementia progression in amnestic mild cognitive impairment...
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