- Bipolar Spectrum: A Review of the Concept and a Vision for the Future
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Ghaemi SN
- KMID: 2316292
- Psychiatry Investig.
- 2013 Sep;10(3):218-224.
This paper reviews the bipolar spectrum concept historically and empirically. It describes how the concept derives from Kraepelin, but was lost with DSM-III, which divided the broad manic-depressive illness concept,... -
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- Is Psychiatry Scientific? A Letter to a 21st Century Psychiatry Resident
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de Leon J
- KMID: 2316291
- Psychiatry Investig.
- 2013 Sep;10(3):205-217.
During the development of the DSM-5, even the lay press questioned psychiatr's scientific validity. This review provides 21st century psychiatry residents with ways of answering these attacks by defining the... -
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- Myasthenia Gravis, Schizophrenia, and Colorectal Cancer in A Patient: Long-Term Follow-Up with Medication Complexity
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Kim H, Hong M, Bahn GH
- KMID: 2316304
- Psychiatry Investig.
- 2013 Sep;10(3):300-302.
In a case of 46-year-old woman suffering from schizophrenia for over 20 years, she experienced frequent episodes of dyspnea and confirmed as superimposed with myasthenia gravis (MG). Throughout the seven-year... -
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- Nocturnal Enuresis Is Associated with Attention Deficit Hyperactivity Disorder and Conduct Problems
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Park S, Kim BN, Kim JW, Hong SB, Shin MS, Yoo HJ, Cho SC
- KMID: 2316297
- Psychiatry Investig.
- 2013 Sep;10(3):253-258.
OBJECTIVE: There are no published prevalence estimates of elimination disorders and their association with disruptive-behavior disorders among children in the Asian region using standardized diagnostic interviews. This study was conducted... -
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- Clinical Usefulness of Loudness Dependence of Auditory Evoked Potentials (LDAEP) in Patients with Bipolar Disorder
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Park YM, Lee SH
- KMID: 2316294
- Psychiatry Investig.
- 2013 Sep;10(3):233-237.
While it has been reported previously that the loudness dependence of auditory evoked potentials (LDAEP) is a putative biological marker or a predictor of treatment response, there have been few... -
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- Decreased Serum Sulphydryl Levels as a Sign of Increased Oxidative Stress in Generalized Anxiety Disorder
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Kaya MC, Bez Y, Karababa I, Emhan A, Aksoy N, Bulut M, Gunes M, Atli A, Selek S
- KMID: 2316301
- Psychiatry Investig.
- 2013 Sep;10(3):281-285.
OBJECTIVE: In recent years, many published studies have focused on the relationship between oxidative stress and psychiatric disorders. However, studies in generalized anxiety disorder (GAD) are few despite relatively high... -
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- Impulsive Behavior and Recurrent Major Depression Associated with Dandy-Walker Variant
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Kim JH, Kim TH, Choi YC, Chung SC, Moon SW
- KMID: 2316305
- Psychiatry Investig.
- 2013 Sep;10(3):303-305.
Reported herein is a case of recurrent major depression with impulse control difficulty in a 33-year-old man with Dandy-Walker variant. He was diagnosed as having major depressive disorder a year... -
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- Circadian Rhythm Hypotheses of Mixed Features, Antidepressant Treatment Resistance, and Manic Switching in Bipolar Disorder
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Lee HJ, Son GH, Geum D
- KMID: 2316293
- Psychiatry Investig.
- 2013 Sep;10(3):225-232.
Numerous hypotheses have been put forth over the years to explain the development of bipolar disorder. Of these, circadian rhythm hypotheses have gained much importance of late. While the hypothalamus-pituitary-adrenal... -
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- Disruption of Orbitofronto-Striatal Functional Connectivity Underlies Maladaptive Persistent Behaviors in Alcohol-Dependent Patients
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Lee S, Lee E, Ku J, Yoon KJ, Namkoong K, Jung YC
- KMID: 2316299
- Psychiatry Investig.
- 2013 Sep;10(3):266-272.
OBJECTIVE: Alcohol dependence is characterized by persistent alcohol-seeking despite negative consequences. Previous studies suggest that maladaptive persistent behaviors reflect alcohol-induced brain changes that cause alterations in the cortico-striatal-limbic circuit. METHODS: Twenty... -
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- Plasma Levels of IL-23 and IL-17 before and after Antidepressant Treatment in Patients with Major Depressive Disorder
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Kim JW, Kim YK, Hwang JA, Yoon HK, Ko YH, Han C, Lee HJ, Ham BJ, Lee HS
- KMID: 2316303
- Psychiatry Investig.
- 2013 Sep;10(3):294-299.
OBJECTIVE: Cytokines are believed to have a role in the pathophysiology of major depression. The alteration in levels of pro-inflammatory cytokines [interleukin 1beta (IL-1beta), IL-2, IL-6, IL-12, interferon gamma, and... -
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- Anti-Intrusion Effect of Lorazepam: An Experimental Study
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Lee HS, Lee HP, Lee SK, Kim YK, Choi YK
- KMID: 2316300
- Psychiatry Investig.
- 2013 Sep;10(3):273-280.
OBJECTIVE: Easy triggering of trauma-related episodic memory fragments caused by perceptual cues is tied to strong perceptual priming in the implicit memory system. And among benzodiazepines, only lorazepam has been... -
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- The Relationship between Impulsivity and Quality of Life in Euthymic Patients with Bipolar Disorder
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Kim YS, Cha B, Lee D, Kim SM, Moon E, Park CS, Kim BJ, Lee CS, Lee S
- KMID: 2316296
- Psychiatry Investig.
- 2013 Sep;10(3):246-252.
OBJECTIVE: Bipolar disorder (BD) is characterized by elevated impulsivity, even during periods of remission. Many recovered BD patients have functional impairments, which can lead to poor quality of life (QoL).... -
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- The Impact of Personality Traits on Ratings of Obsessive-Compulsive Symptoms
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Huh MJ, Shim G, Byun MS, Kim SN, Kim E, Jang JH, Shin MS, Kwon JS
- KMID: 2316298
- Psychiatry Investig.
- 2013 Sep;10(3):259-265.
OBJECTIVE: The goal of this study was to evaluate consistencies and discrepancies between clinician-administered and self-report versions of the Yale-Brown Obsessive Compulsive Scale (Y-BOCS) and to examine relationships between these... -
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- CYP2D6 P34S Polymorphism and Outcomes of Escitalopram Treatment in Koreans with Major Depression
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Han KM, Chang HS, Choi IK, Ham BJ, Lee MS
- KMID: 2316302
- Psychiatry Investig.
- 2013 Sep;10(3):286-293.
OBJECTIVE: Cytochrome P450 (CYP) enzymatic activity, which is influenced by CYP genetic polymorphism, is known to affect the inter-individual variation in the efficacy and tolerability of antidepressants in major depressive... -
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- Validation of the Dementia Care Assessment Packet-Instrumental Activities of Daily Living
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Lee SB, Park JR, Yoo JH, Park JH, Lee JJ, Yoon JC, Jhoo JH, Lee DY, Woo JI, Han JW, Huh Y, Kim TH, Kim KW
- KMID: 2316295
- Psychiatry Investig.
- 2013 Sep;10(3):238-245.
OBJECTIVE: We aimed to evaluate the psychometric properties of the IADL measure included in the Dementia Care Assessment Packet (DCAP-IADL) in dementia patients. METHODS: The study involved 112 dementia patients and... -
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