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Differentiation characteristics of cholesteatoma epithelium determined by expression of transglutaminase isoenzymes

Chang CS, Jun BH, Song KY, Kim IG

Transglutaminase (TGase) isoenzymes are involved in the process of the differentiation and cornification of keratinocytes in the epidermis. This study investigates the presence and localization of three TGase isoenzymes to...
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Calpain inhibitors reduce the cornified cell envelope formation by inhibiting proteolytic processing of transglutaminase 1

Kim SY, Bae CD

  • KMID: 755018
  • Exp Mol Med.
  • 1998 Dec;30(4):257-262.
Calpain I (mu-calpain) and II (m-calpain) are well known calcium-activated neutral cysteine proteases. Many reports have shown that activation of calpain is related to cataract formation, neuronal degeneration, blood clotting, ...
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A new member of alpha 1-adrenoceptor-coupled G alpha h (transglutaminase II) family in pig heart: purification and characterization

Yoo SM, Jeong HS, Han KJ, Cho SH, Lee HS, Yun HY, Kwon NS, Baek KJ

  • KMID: 754992
  • Exp Mol Med.
  • 1998 Jun;30(2):81-86.
We previously reported an identification of a 77-kDa GTP-binding protein that co-purified with the alpha 1-adrenoceptor following ternary complex formation. In the present paper, we report on the purification and characterization of...
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Bricks and mortar of the epidermal barrier

Nemes Z, Steinert P

  • KMID: 755021
  • Exp Mol Med.
  • 1999 Mar;31(1):5-19.
A specialized tissue type, the keratinizing epithelium, protects terrestrial mammals from water loss and noxious physical, chemical and mechanical insults. This barrier between the body and the environment is constantly maintained by reproduction...
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