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Aberrant Cell Cycle Regulation in Cervical Carcinoma

Kim YT, Zhao M

Carcinoma of the uterine cervix is one of the most common malignancies among women worldwide. Human papillomaviruses (HPV) have been identified as the major etiological factor in cervical carcinogenesis. However,...
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Potentials and limitations of adenovirus-p53 gene therapy for brain tumors

Hong YK, Joe YA, Yang YJ, Lee KS, Son BC, Jeun SS, Chung DS, Cho KK, Park CK, Kim MC, Kim HK, Yung WK, Kang JK

We investigated the antineoplastic potentials of recombinant adenovirus containing wild-type p53 cDNA (Ad5CMV-p53) for malignant gliomas. In four human glioma cell lines (U-251 and LG expressing endogenous mutant p53, and...
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Induction of apoptosis in colon cancer cells by nonsteroidal anti-inflammatory drugs

Hong SP, Ha SH, Park IS, Kim WH

Epidemiological studies have demonstrated that nonsteroidal anti-inflammatory drugs (NSAIDs) decrease the incidence of colon cancer. In addition, NSAIDs reduce the number and size of polyps in patients with familial adenomatous...
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