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Coexpression of MUC1 with p53 or MUC2 correlates with Lymph Node Metastasis in Colorectal Carcinomas

Jang KT, Chae SW, Sohn JH, Park HR, Shin HS

The alteration of the mucin profile have been known to play a role in colorectal carcinogenesis. MUC1 is up-regulated and MUC2 is down-regulated in colorectalcarcinomas. Overexpression of p53 is frequently...
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Clinical Prognostic Values of Vascular Endothelial Growth Factor, Microvessel Density,and p53 Expression in Esophageal Carcinomas

Ahn MJ, Jang SJ, Park YW, Choi JH, Oh HS, Lee CB, Paik HK, Park CK

Vascular endothelial growth factor (VEGF) is known to play a key role in tumor angiogenesis. The tumor-suppressor gene p53 has been thought to regulate VEGF. We investigated the effect of...
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Thyroid Transcription Factor-1 (TTF-1) Expression in Human Lung Carcinomas: Its Prognostic Implication and Relationship with Expressions of p53 and Ki-67 Proteins

Myong NH

This study was aimed to evaluate the prevalence and prognostic implication of thyroid transcription factor-1 (TTF-1) immunoreactivity in 81 human lung carcinomas, including 65 cases of non-small cell lung carcinoma...
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Altered p53 expression in Epstein Barr virus positive T cell lymphomas

Lee JH, Lee SS, Park JS, Lee S, Yang MH, Yoon TY

Recent studies have suggested a probable association between Epstein-Barr virus (EBV) and nasal/nasopharyngeal T cell lymphomas but the role of oncogenes or tumor suppressor genes is poorly understood. We have...
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Mutation and overexpression of p53 as a prognostic factor in canine mammary tumors

Lee CH, Kim WH, Lim JH, Kang MS, Kim DY, Kweon OK

  • KMID: 1094689
  • J Vet Sci.
  • 2004 Mar;5(1):63-69.
We concentrated ourselves to evaluate the prognostic significance of the p53 gene mutations, its protein expression and MIB-1 index as a proliferative marker in canine mammary tumors. In the present...
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The Role of Vascular Endothelial Growth Factor (VEGF) and p53 Status for Angiogenesis in Gastric Cancer

Joo YE, Sohn YH, Joo SY, Lee WS, Min SW, Park CH, Rew JS, Choi SK, Park CS, Kim YJ, Kim SJ

  • KMID: 759613
  • Korean J Intern Med.
  • 2002 Dec;17(4):211-219.
BACKGROUND: Angiogenesis is of crucial importance for tumor growth and development of metastases. Vascular endothelial growth factor (VEGF) has a potent angiogenic activity and mutations of the p53 gene...
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Correlation of Mutation and Immunohistochemistry of p53 in Hepatocellular Carcinomas in Korean People

Lee SN, Park CK, Sung CO, Choi JS, Oh YL, Cho JW, Yoo BC

The degree of correlation between sequencing and immunohistochemisty (IHC) for detecting mutations of p53 has not been well established in human hepatocellular carcinoma (HCC). We analyzed 36 HCCs from...
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