- 5' CpG island methylation of p16 is associated with absence of p16 expression in glioblastomas
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Park SH, Jung KC, Ro JY, Kang GH, Khang SK
- KMID: 965879
- J Korean Med Sci.
- 2000 Oct;15(5):555-559.
- doi: 10.3346/jkms.2000.15.5.555
Recent evidence shows that transcriptional silencing as a consequence of hypermethylation of CpG islands is an important mechanism in the inactivation of p16INK4 tumor suppressor gene. This study is designed... -
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- Clinical significance of molecular genetic changes in sporadic invasive pituitary adenomas
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Nam DH, Song SY, Park KS, Kim MH, Suh YL, Lee JI, Kim JS, Hong SC, Shin HJ, Park K, Eoh W, Kim JH
- KMID: 938873
- Exp Mol Med.
- 2001 Sep;33(3):111-116.
Several molecular and genetic changes have been found in pituitary adenomas. We looked for correlations between these changes and the degree of invasiveness of the tumors. The invasiveness of 11... -
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- Alterations of CDKN2 (MTS1/p16INK4A) gene in paraffin-embedded tumor tissues of human stomach, lung, cervix and liver cancers
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Kim JR, Kim SY, Kim MJ, Kim JH
- KMID: 754996
- Exp Mol Med.
- 1998 Jun;30(2):109-114.
The CDKN2 (MTS1/p16INK4A) gene, encoding cyclin dependent kinase inhibitor, was found to be homozygously deleted at a high frequency in cell lines from many different types of cancer and some primary cancers.... -
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- Cellular characteristics of primary and immortal canine embryonic fibroblast cells
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You S, Moon JH, Kim TK, Kim SC, Kim JW, Yoon DH, Kwak S, Hong KC, Choi YJ, Kim H
- KMID: 1094076
- Exp Mol Med.
- 2004 Aug;36(4):325-335.
Using normal canine embryonic fibroblasts (CaEF) that were shown to be senescent at passages 7th-9th, we established two spontaneously immortalized CaEF cell lines (designated CGFR-Ca-1 and -2) from normal senescent... -
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