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The p38 mitogen-activated protein kinase is involved in stress-induced phospholipase D activation in vascular smooth muscle cells

Min DS, Shin EY, Kim EG

  • KMID: 1093596
  • Exp Mol Med.
  • 2002 Mar;34(1):38-46.
Oxidative stress has been implicated in mediation of vascular disorders. Earlier study showed that the exposure of vascular smooth muscle cells (VSMC) to pervanadate (hydrogen peroxide plus orthovanadate) resulted in...
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Interleukin-1beta stimulates matrix metalloproteinase-2 expression via a prostaglandin E2-dependent mechanism in human chondrocytes

Choi YA, Lee DJ, Lim HK, Jeong JH, Sonn JK, Kang SS, Baek SH

  • KMID: 1097104
  • Exp Mol Med.
  • 2004 Jun;36(3):226-232.
IL-1beta is known promote cyclooxygenase-2 (COX- 2) and matrix metalloproteinase-2 (MMP-2) expression. This study focuses on the characterization of the signaling cascade associated with IL-1beta-induced matrix metalloproteinase-2 (MMP- 2) regulation...
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Morphine Postconditioning Attenuates ICAM-1 Expression on Endothelial Cells

Min TJ, Kim JI, Kim JH, Noh KH, Kim TW, Kim WY, Lee YS, Park YC

The purpose of this study is to determine 1) whether morphine postconditiong (MPostC) can attenuate the intercellular adhesion molecules-1 (ICAM-1) expression after reoxygenation injury and 2) the subtype(s) of the...
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