- Phosphorylation of glycogen synthase kinase-3beta at serine-9 by phospholipase Cgamma1 through protein kinase C in rat 3Y1 fibroblasts
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Shin SY, Yoon SC, Kim YH, Kim YS, Lee YH
- KMID: 1121098
- Exp Mol Med.
- 2002 Dec;34(6):444-450.
Phospholipase Cgamma1 (PLCgamma1) plays an important role in controlling cellular proliferation and differentiation. PLCgamma1 is overexpressed in some tumors, and its overexpression induces solid tumors in nude mice. However,... -
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- Protein kinase C modulates telomerase activity in human cervical cancer cells
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Kim YW, Hur SY, Kim TE, Lee JM, Namkoong S, Ki IK, Kim JW
- KMID: 938880
- Exp Mol Med.
- 2001 Sep;33(3):156-163.
Telomerase, a ribonucleoprotein reverse transcriptase that extends telomeres of eukaryotic chromosomes is repressed in normal somatic cells but is activated during development and neoplasia. The regulation mechanism of telomerase activity... -
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- Deoxyhypusine synthase is phosphorylated by protein kinase C in vivo as well as in vitro
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Kang KR, Kim JS, Chung SI, Park MH, Kim YW, Lim DK, Lee SY
- KMID: 1121104
- Exp Mol Med.
- 2002 Dec;34(6):489-495.
Deoxyhypusine synthase catalyzes the first step in the posttranslational synthesis of an unusual amino acid, hypusine, in the eukaryotic translation initiation factor 5A (eIF-5A) precursor protein. We earlier observed... -
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