- Challenges and New Approaches in Genomics and Bioinformatics
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Park JH, Han KS
- KMID: 1973989
- Genomics Inform.
- 2003 Sep;1(1):1-6.
No abstract available. -
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- GSnet: An Integrated Tool for Gene Set Analysis and Visualization
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Choi YJ, Woo HG, Yu U
- KMID: 2166269
- Genomics Inform.
- 2007 Sep;5(3):133-136.
The Gene Set network viewer (GSnet) visualizes the functional enrichment of a given gene set with a protein interaction network and is implemented as a plug-in for the Cytoscape platform.... -
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- CTCF as a multifunctional protein in genome regulation and gene expression
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Kim S, Yu NK, Kaang BK
- KMID: 2155420
- Exp Mol Med.
- 2015 Jun;47(6):e166.
- doi: 10.1038/emm.2015.33
CCCTC-binding factor (CTCF) is a highly conserved zinc finger protein and is best known as a transcription factor. It can function as a transcriptional activator, a repressor or an insulator... -
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- Phospholipase D2 promotes degradation of hypoxia-inducible factor-1alpha independent of lipase activity
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Park MH, Bae SS, Choi KY, Min DS
- KMID: 2359883
- Exp Mol Med.
- 2015 Nov;47(11):e196.
- doi: 10.1038/emm.2015.87
Hypoxia-inducible factor-1alpha (HIF-1alpha) is a key transcriptional mediator that coordinates the expression of various genes involved in tumorigenesis in response to changes in oxygen tension. The stability of HIF-1alpha protein... -
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- The biological complexity of RKIP signaling in human cancers
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Farooqi AA, Li Y, Sarkar FH
- KMID: 2155439
- Exp Mol Med.
- 2015 Sep;47(9):e185.
- doi: 10.1038/emm.2015.70
The Raf kinase inhibitory protein (RKIP) has been demonstrated to modulate different intracellular signaling pathways in cancers. Studies have shown that RKIP is frequently downregulated in cancers; therefore, attempts have... -
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- N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points
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Islam MA, Sharif SR, Lee H, Seog DH, Moon IS
- KMID: 2155431
- Exp Mol Med.
- 2015 Aug;47(8):e177.
- doi: 10.1038/emm.2015.48
N-acetylglucosamine kinase (GlcNAc kinase or NAGK) is a ubiquitously expressed enzyme in mammalian cells. Recent studies have shown that NAGK has an essential structural, non-enzymatic role in the upregulation of... -
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- Profiling of remote skeletal muscle gene changes resulting from stimulation of atopic dermatitis disease in NC/Nga mouse model
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Lee D, Seo Y, Kim YW, Kim S, Choi J, Moon SH, Bae H, Kim HS, Kim H, Kim JH, Kim TY, Kim E, Yim S, Lim I, Bang H, Kim JH, Ko JH
- KMID: 2455813
- Korean J Physiol Pharmacol.
- 2019 Sep;23(5):367-379.
- doi: 10.4196/kjpp.2019.23.5.367
Although atopic dermatitis (AD) is known to be a representative skin disorder, it also affects the systemic immune response. In a recent study, myoblasts were shown to be involved in... -
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- APE1/Ref-1 as an emerging therapeutic target for various human diseases: phytochemical modulation of its functions
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Thakur S, Sarkar B, Cholia RP, Gautam N, Dhiman M, Mantha AK
- KMID: 2155371
- Exp Mol Med.
- 2014 Jul;46(7):e106.
- doi: 10.1038/emm.2014.42
Apurinic/apyrimidinic endonuclease 1 (APE1) is a multifunctional enzyme involved in the base excision repair (BER) pathway, which repairs oxidative base damage caused by endogenous and exogenous agents. APE1 acts as... -
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