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Structural Bioinformatics Analysis of Disease-related Mutations

Park SJ, Oh S, Park D, Bhak J

  • KMID: 2166411
  • Genomics Inform.
  • 2008 Sep;6(3):142-146.
In order to understand the protein functions that are related to disease, it is important to detect the correlation between amino acid mutations and isease. Many mutation studies about disease-related...
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Effects of overexpression of stimulatory G proteins on the expression of the other G proteins in COS-1 cells

Kim SY, Jang IS, Yang JM, Kwak SJ, Juhnn YS

  • KMID: 2045610
  • Exp Mol Med.
  • 1997 Jun;29(2):133-137.
To investigate the interaction of stimulatory GTP binding protein (G(s)) pathways with others, we overexpressed wild type alpha subunit of G(s) (G(s) alpha), constitutively activated R201E G(s) alpha, and dominant...
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Expression of a recombinant branched chain alpha-oxo acid dehydrogenase complex E2 (BCOADC-E2) in insect cells and its immunoreactivity to autoimmune sera

Lee SM, Ko SH, Park JE, Cha SH

  • KMID: 754990
  • Exp Mol Med.
  • 1998 Jun;30(2):65-71.
Preparation of a pure autoantigen by way of recombinant DNA technology has an important value in an accurate diagnosis or prognosis of an autoimmune disease. BCOADC-E2 subunit, a mitochondrial protein, has been...
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