- Mechanisms of aging-related proteinopathies in Caenorhabditis elegans
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Kim DK, Kim TH, Lee SJ
- KMID: 2361550
- Exp Mol Med.
- 2016 Oct;48(10):e263.
- doi: 10.1038/emm.2016.109
Aging is the most important risk factor for human neurodegenerative diseases such as Alzheimer's and Parkinson's diseases. Pathologically, these diseases are characterized by the deposition of specific protein aggregates in... -
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- Phagocytic Roles of Glial Cells in Healthy and Diseased Brains
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Jung YJ, Chung WS
- KMID: 2420385
- Biomol Ther.
- 2018 Jul;26(4):350-357.
- doi: 10.4062/biomolther.2017.133
Glial cells are receiving much attention since they have been recognized as important regulators of many aspects of brain function and disease. Recent evidence has revealed that two different glial... -
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- Docosahexaenoic acid-mediated protein aggregates may reduce proteasome activity and delay myotube degradation during muscle atrophy in vitro
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Shin SK, Kim JH, Lee JH, Son YH, Lee MW, Kim HJ, Noh SA, Kim KP, Kim IG, Lee MJ
- KMID: 2367533
- Exp Mol Med.
- 2017 Jan;49(1):e287.
- doi: 10.1038/emm.2016.133
Proteasomes are the primary degradation machinery for oxidatively damaged proteins that compose a class of misfolded protein substrates. Cellular levels of reactive oxygen species increase with age and this cellular... -
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