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Sox-4 is a positive regulator of Hep3B and HepG2 cells' apoptosis induced by prostaglandin (PG)A2 and 12-PGJ2.

Ahn SG, Kim HS, Jeong SW, Kim BE, Rhim HS, Shim JY, Kim JW, Lee JH, Kim IK

  • KMID: 1380233
  • Exp Mol Med.
  • 2002 Jul;34(3):243-249.
We reported earlier that expression of Sox-4 was found to be elevated during prostaglandin (PG) A2 and delta(12)-PGJ(12) induced apoptosis in human hepatocarcinoma Hep3B cells. In this study, the role...
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Prostaglandin A2 Induces Caspase-independent Apoptosis in Hepatocellular Carcinoma Cells

Kim HS, Shim JC, Choi JY, Rhim H, Kim IK

  • KMID: 760582
  • Korean J Hepatol.
  • 2005 Mar;11(1):72-79.
BACKGROUND/AIMS: Prostaglandin (PG) A2 has been reported to inhibit the growth of hepatocellular carcinoma cells via activation of apoptosis, although the molecular mechanisms involved have not been clarified, yet....
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