- Fenofibrate inhibits adipocyte hypertrophy and insulin resistance by activating adipose PPARalpha in high fat diet-induced obese mice
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Jeong S, Yoon M
- KMID: 756232
- Exp Mol Med.
- 2009 Jun;41(6):397-405.
- doi: 10.3858/emm.2009.41.6.045
Peroxisome proliferator-activated receptor alpha (PPARalpha) activation in rodents is thought to improve insulin sensitivity by decreasing ectopic lipids in non-adipose tissues. Fenofibrate, a lipid-modifying agent that acts as a PPARalpha... -
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- The Increase in Hepatic Uncoupling by Fenofibrate Contributes to a Decrease in Adipose Tissue in Obese Rats
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Park MK, Lee HJ, Hong SH, Choi SS, Yoo YH, Lee KI, Kim DK
- KMID: 1713174
- J Korean Med Sci.
- 2007 Apr;22(2):235-241.
- doi: 10.3346/jkms.2007.22.2.235
Fenofibrate is a drug that has been suggested to inhibit weight gain by increasing the catabolism of fatty acid in the hepatic mitochondria. We hypothesized that fenofibrate induces an increase... -
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- Fenofibrate regulates obesity and lipid metabolism with sexual dimorphism
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Yoon MC, Jeong SH, Nicol CJ, Lee HH, Han MY, Kim JJ, Seo YJ, Ryu CY, Oh GT
- KMID: 1121103
- Exp Mol Med.
- 2002 Dec;34(6):481-488.
To determine whether the PPARalpha agonist fenofibrate regulates obesity and lipid metabolism with sexual dimorphism, we examined the effects of fenofibrate on body weight, white adipose tissue (WAT) mass,... -
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