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Monogenic diabetes: recent updates on diagnosis and precision treatment: A narrative review

Jang KM

Monogenic diabetes is commonly caused by single-gene mutations. This disease ranges from 1% to 5% in all cases of diabetes and is less affected by behavior and environment. Neonatal diabetes...
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The genetics of obesity: A narrative review

Sohn YB

Monogenic obesity is a rare, early-onset, and severe form of obesity that has a Mendelian inheritance pattern, high penetrance, and large genetic effect. In contrast, common polygenic obesity is more...
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Clinical effectiveness and prospects of methylene blue: A systematic review

Seitkazina A, Yang JK, Kim S

Methylene blue (MB) is a well-known pharmaceutical ingredient that is thought to have a multi-targeted therapeutic effect as an anti-malarial and neuroprotective agent and has recently been identified as a...
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A new era of genetic diagnosis for short stature children: A review

Kim YM

Children with short stature are often presented to pediatric endocrinologists. Short stature is defined as the height that is more than two standard deviations below the corresponding mean height for...
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Evaluation of MET alteration in EGFR-mutant non-small cell lung cancer patients treated with EGFR tyrosine kinase inhibitor from paired biopsy: A retrospective cohort study

Ku BM, Park S, Park S, Jung HA, Sun JM, Lee SH, Ahn JS, Choi YL, Ahn MJ

Purpose: Mesenchymal-epithelial transition tyrosine kinase receptor (MET) amplification is one of the common acquired resistance mechanisms to epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor (TKI). To evaluate the usefulness...
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