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Telomerase is strongly activated in hepatocellular carcinoma but not in chronic hepatitis and cirrhosis

Park YM, Choi JY, Byun BH, Cho CH, Kim HS, Kim BS

  • KMID: 754985
  • Exp Mol Med.
  • 1998 Mar;30(1):35-40.
Telomerase is highly activated in human immortal cell lines and tumor tissues, whereas it is not activated in primary cell strains and many tumor-adjacent tissues. It is suggested that telomerase activation is...
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Helicobacter pylori and Telomerase Activity in Intestinal Metaplasia of the Stomach

Chung IK, Hwang KY, Kim IH, Kim HS, Park SH, Lee MH, Kim CJ, Kim SJ

  • KMID: 759615
  • Korean J Intern Med.
  • 2002 Dec;17(4):227-233.
BACKGROUND: Helicobacter pylori (H. pylori) has been considered a definitive carcinogen in gastric cancer. Telomerase is activated in gastric cancer and some premalignant gastric lesions, including intestinal metaplasia (IM)....
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Immunohistochemical Analysis of Nuclear Factor, p38, and Cyclin D1 Proteins in Premalignant Lesions and Carcinomas of the Colorectal Mucosa

Lee SD, Lee TJ, Park ES

  • KMID: 783112
  • Korean J Gastroenterol.
  • 2008 Dec;52(6):359-367.
BACKGROUND/AIMS: Nuclear factor-kappa B p65 (NF-kappa B p65), nuclear factor-kappa B1 p50 (NF-kappa B p50) have been shown to play a role in cell proliferation, apoptosis, cytokine production, and oncogenesis....
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