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The Impact of Opioid Treatment on Regional Gastrointestinal Transit

Poulsen JL, Nilsson M, Brock C, Sandberg T, Krogh K, Drewes AM

  • KMID: 2203582
  • J Neurogastroenterol Motil.
  • 2016 Apr;22(2):282-291.
  • doi: 10.5056/jnm15175
BACKGROUND/AIMS: To employ an experimental model of opioid-induced bowel dysfunction in healthy human volunteers, and evaluate the impact of opioid treatment compared to placebo on gastrointestinal (GI) symptoms and motility...
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Colorectal Transit and Volume During Treatment With Prolonged-release Oxycodone/Naloxone Versus Oxycodone Plus Macrogol 3350

Poulsen JL, Mark EB, Brock C, Frøkjær , Krogh K, Drewes AM

  • KMID: 2417279
  • J Neurogastroenterol Motil.
  • 2018 Jan;24(1):119-127.
  • doi: 10.5056/jnm17058
BACKGROUND/AIMS: Opioid-induced constipation (OIC) is the most common gastrointestinal (GI) side effect to opioid treatment. Opioid receptor antagonists against OIC have been introduced, but their efficacy has not been directly...
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