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Polyubiquitin chain-dependent protein degradation in TRIM30 cytoplasmic bodies

Choi UY, Choi WY, Hur JY, Kim YJ

Viral infection induces numerous tripartite motif (TRIM) proteins to control antiviral immune signaling and viral replication. Particularly, SPRY-containing TRIM proteins are found only in vertebrates and they control target protein...
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Cloning of Novel Ubiquitin Conjugating Enzyme Gene(UBC-dp)

Lee JW, Song KE, Suh JS, Lee WK, Kwon JS, Kim JS, Kim MK, Kim JC

  • KMID: 2039334
  • Korean J Clin Pathol.
  • 1997 Feb;17(1):190-199.
BACKGROUND: A major pathway for protein degradation in eukaryocytes is ubiquitin-dependent. A novel species of plant and mammalian E2 homologous to yeast UBC4/UBC5 is involved in polyubiquitination and degradation of...
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ATP13A2/PARK9 Deficiency Neither Cause Lysosomal Impairment Nor Alter alpha-Synuclein Metabolism in SH-SY5Y Cells

Bae EJ, Lee C, Lee HJ, Kim S, Lee SJ

Parkinson's disease is a multifactorial disorder with several genes linked to the familial types of the disease. ATP13A2 is one of those genes and encode for a transmembrane protein localized...
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