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Effect of Poloxamer-Based ThermoSensitive Sol-Gel Agent on Upper Limb Dysfunction after Axillary Lymph Node Dissection: A Double-Blind Randomized Clinical Trial

Choi HJ, Ryu JM, Chae BJ, Kim EK, Min JW, Shin HJ, Nam SJ, Yu J, Lee JE, Lee SK, Kim SW

Purpose: Restricted shoulder motion is a major morbidity associated with a lower quality of life and disability after axillary lymph node dissection (ALND) in patients with breast cancer. This study sought...
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Berberine Ameliorates Brain Inflammation in Poloxamer 407-Induced Hyperlipidemic Rats

Kim M, Kim TW, Kim CJ, Shin MS, Hong M, Park HS, Park SS

PURPOSE: Hyperlipidemia, which promotes the development of atherosclerosis, ischemic stroke, and other forms of brain injury, can be induced by poloxamer-407. Berberine is a primary pharmacological active component of Coptidis...
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Poloxamer 407 Hydrogels for Intravesical Instillation to Mouse Bladder: Gel-Forming Capacity and Retention Performance

Kim SH, Kim SR, Yoon HY, Chang IH, Whang YM, Cho MJ, Kim MJ, Kim SY, Lee SJ, Choi YW

PURPOSE: Poloxamer 407 (P407) thermo-sensitive hydrogel formulations were developed to enhance the retention time in the urinary bladder after intravesical instillation. MATERIALS AND METHODS: P407 hydrogels (P407Gels) containing 0.2 w/w% fluorescein...
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The Effect of Poloxamer 407-Based Hydrogel on the Osteoinductivity of Demineralized Bone Matrix

Lee JH, Baek HR, Lee KM, Lee HK, Im SB, Kim YS, Lee JH, Chang BS, Lee CK

BACKGROUND: Demineralized bone matrix (DBM) is used for bone healing due to its osteoinductivity, but it requires a carrier for clinical application. Here, we report the effects on the osteoinductivity...
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Anti-adhesive Effect of Poloxamer/Alginate/CaCl2 Mixture in the Rat Model

Kwon SW, Lim SH, Lee YW, Lee YG, Chu BY, Lee JH, Lee YM

  • KMID: 1844904
  • J Korean Surg Soc.
  • 2006 Oct;71(4):280-287.
PURPOSE: The occurrence of post-surgical adhesion is still a major cause of postoperative morbidity due to the lack of satisfactory treatment or prophylaxis. Several adhesion barriers have been developed in...
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IrreVersible Gel Tansformation of Injectavble Intraocular Lens by Photoinitiator and UV Irradiation in Rabbits

Kwon JW, Han YK, Lee W, Kim HY, Kim JS, Cho CS, Paik SJ, Byun SW, Cho DI, Lee JH, Wee WR

  • KMID: 2337149
  • J Korean Ophthalmol Soc.
  • 2004 Sep;45(9):1535-1540.
PURPOSE: This study was designed to induce irreVersible gel formation of poloxamer, the thermosensitive polymer hydrogel, by using photoinitiator and UV irradiation, and to verify the biocompatibility and usability of...
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The Development of Injectable Intraocular Lens Using Thermosensitive Polymeric Hydrogel in Vitro and in Vivo

Han YK, Kwon JW, Kim HY, Kim JS, Cho CS, Wee WR, Lee JH

  • KMID: 2206692
  • J Korean Ophthalmol Soc.
  • 2003 Sep;44(9):2137-2143.
PURPOSE: To evaluate the compatibility of poloxamer hydrogel as a material for the injectable intraocular lens in in vivo and in vitro model. METHODS: We determined the appropriate concentration of...
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An Experimental Study on the Wound Healing Effects of Recombinant Human Epidermal Growth Factors According to Poloxamer Concentrations in Full-thickness Excisional Wound Models of Rats

Baek RM, Chung WJ, Lee YJ, Lee JH, Im TG, Yoon BH

  • KMID: 2098271
  • J Korean Soc Plast Reconstr Surg.
  • 2003 Mar;30(2):209-216.
This study was designed to investigate the optimal poloxamer concentration in the mixed solution of recombinant human epidermal growth factor and poloxamer which can be effective in the wound healing...
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The Experimental Study Using Beagle Dogs for the Clinical Application of Poloxamer-solutol Propofol

Ahn HH, Choi SH, Lee SK, Kim YM, Song HJ, Moon HS, Kil HY

BACKGROUND: To reduce side effects such as hyperlipidemia, pain on injection, and bacterial growth of the present formation of propofol, many attempts to change its formulation have been tried. We...
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The Comparison for the Growth of Microorganisms in Original Propofol, Ethylenediaminetetraacetic Acid (EDTA) Added Propofol, and Poloxamer-Solutol Formulated Propofol

Kil HY, Ahn HH

BACKGROUND: Because there is difficulty in the addition of known preservatives to oil in water emulsion such as propofol, ethylenediaminetetraacetic acid (EDTA) added to this may formulate for the antimicrobial...
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Comparison of Poloxamer-407 to Soybean Oil as an Emulsifying Agent for Propofol: Histamine Release and Plasma Lipid Levels

Lee HH, Kil HY, Han TH, Park H, Shin SI, Yang HJ, Kim MK, Kim DW

BACKGROUND: To reduce side effects (hyperlipidemia, pain on injection, etc.) of the present formation of propofol, many attempts to change the emulsifying agent for propofol have been tried. This...
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