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Clinical application of preimplantation genetic diagnosis (PGD) using fluorescence in-situ hybridization to balanced reciprocal or Robertsonian translocation carriers in human IVF-ET program

Jun JH, Song GJ, Kim JW, Park SY, Kim KH, Choi BC, Koong MK, Kang IS, Lim CK, Han MH

  • KMID: 2262031
  • Korean J Obstet Gynecol.
  • 2000 Jul;43(7):1147-1153.
OBJECTIVE: This study was performed to evaluate the efficiency of preimplantation genetic diagnosis (PGD) using fluorescence in-situ hybridization (FISH) in Robertsonian or balanced reciprocal translocation carriers in human IVF-ET programm. METHOD: FISH...
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Fertilization and pregnancy potential of immature oocytes from stimulated intracytoplasmic sperm injection cycles

Shin SB, Cho JW, Lee SH, Yang KM, Lim CK, Lee HS

OBJECTIVE: We evaluated the fertilization potential of immature oocytes obtained from controlled ovarian hyperstimulation cycles of patients undergoing ICSI. METHODS: We retrospectively analyzed 463 ICSI cycles containing at least one immature...
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Expression of OB-R, Regulation of Mitogen Activated Protein Kinase Activity and Maturation by Leptin in Mouse Oocytes

Kang BM, Han HJ, Seo HY, Hong SH, Gye MC

  • KMID: 1891260
  • Korean J Fertil Steril.
  • 2001 Jun;28(2):111-120.
OBJECTIVE: To verify the expression of leptin receptor (OB-R) in oocytes and preimplantation embryos, the involvement of mitogen activated protein kinase (MAPK or Erk1/2) in the leptin signaling, and effect...
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Effects of Melatonin on the Meiotic Maturation of Mouse Oocytes in vitro

Ahn HJ, Bae IH

  • KMID: 2085162
  • Korean J Fertil Steril.
  • 2004 Sep;31(3):155-168.
OBJECTIVE: Melatonin, which is secreted by pineal gland play an important role in the regulation of ovarian function via seasonal rhythm and sleep in most mammals. It also has a...
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Oocyte maturity in repeated ovarian stimulation

Lee JE, Kim SD, Jee BC, Suh CS, Kim SH

OBJECTIVE: During stimulated IVF cycles, up to 15% of oocytes are recovered as immature. The purpose of this study was to investigate the trend of oocyte maturity in repeated ovarian...
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Analyses of Dystrophin Gene and Sex Determination using PEP-PCR in Single Fetal Cells

Choi SK, Kim JW, Cho EH, Park SY, Ryu HM, Kang IS

  • KMID: 1930556
  • Korean J Fertil Steril.
  • 1997 Apr;24(1):51-56.
Recently, through the development of the primer extension preamplification(PEP) method which amplifies the whole genome, simultaneous multiple DNA analysis has become possible. Whole genome from each single cell can be...
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Fertilization and embryo quality of mature oocytes with specific morphological abnormalities

Yu EJ, Ahn H, Lee JM, Jee BC, Kim SH

OBJECTIVE: To investigate fertilization and embryo quality of dysmorphic mature oocytes with specific morphological abnormalities obtained from intracytoplasmic sperm injection (ICSI). METHODS: The fertilization rate (FR) and embryo quality were compared...
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Effects of Nitric Oxide on the Maturation of Mouse Oocyte in vitro

Kim JL, Lee KY, Park HJ, Kwon YS, Lee YI

  • KMID: 2075948
  • Korean J Obstet Gynecol.
  • 1999 Nov;42(11):2542-2548.
OBJECTIVE: Nitric oxide (NO) produced in ovary may contribute to follicle maturation, ovulation, oocyte maturation and luteinization. In this study, the effect of nitric oxide on the spontaneous maturation of...
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Correlations between embryo morphokinetic development and maternal age: Results from an intracytoplasmic sperm injection program

Faramarzi , Khalili MA, Mangoli E

OBJECTIVE: It is widely accepted that aging decreases women’s fertility capacity. The aim of this study was to assess correlations between maternal age and the morphokinetic parameters and cleavage pattern...
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Morphologic Parameters and in vitro Maturational Competence of Human Immature Oocyte Obtained from Stimulated IVF Cycle

An SJ, Jee BC, Moon JH, Lee JR, Suh CS, Kim SH

  • KMID: 1483326
  • Korean J Reprod Med.
  • 2008 Dec;35(4):285-291.
OBJECTIVE: This study was performed to investigate whether cumulus morphology and oocyte diameter influence on in vitro maturation (IVM) of human germinal vesicle (GV) stage oocytes obtained from stimulated in...
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An update of preimplantation genetic diagnosis in gene diseases, chromosomal translocation, and aneuploidy screening

Chang LJ, Chen SU, Tsai YY, Hung CC, Fang MY, Su YN, Yang YS

Preimplantation genetic diagnosis (PGD) is gradually widely used in prevention of gene diseases and chromosomal abnormalities. Much improvement has been achieved in biopsy technique and molecular diagnosis. Blastocyst biopsy can...
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