- Clinical Features of Hypersensitivity Reactions to Cisplatin and Carboplatin
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Park YJ, Moon EJ, Chung HH, Roh JW, Park SY, Park YS
- KMID: 2272046
- Korean J Obstet Gynecol.
- 2003 May;46(5):1018-1023.
OBJECTIVE: To characterize the clinical features of platinum compounds (cisplatin plus carboplatin) associated hypersensitivity reactions. METHODS: Medical records of 102 patients with gynecologic malignancy who received chemotherapy based on platinum at... -
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- Selective Cytotoxicity of Novel Platinum (II) Coordination Complexes on Human Bladder Cancer Cell-Lines and Normal Kidney Cells
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Kim JT, Rho YS, Jung JC
- KMID: 2285285
- Korean J Physiol Pharmacol.
- 2003 Apr;7(2):111-117.
Cisplatin is often effective in cancer treatment, but its clinical use is limited because of its nephrotoxicity. We have synthesized new platinum (II) coordination complexes (PC-1 & PC-2) containing trans-l... -
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- Lethal Effects of Radiation and Platinum Analogues on Multicellular Spheroids of HeLa Cells
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Hong SE
- KMID: 2197189
- J Korean Soc Ther Radiol.
- 1989 Dec;7(2):149-156.
Multicellul ar tumor spheroids of HeLa cells have been grown in a static culture system. Samples of spheroids were exposed for 2 h to graded concentration of sis-platinum and its... -
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- Delay of the Blink Reflex in Patients Receiving Platinum-Analogue Chemotherapy
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Park KY, Park YS, Park YH, Chang HJ, Cho ES, Kim SH, Kim WJ
- KMID: 2155167
- Ann Rehabil Med.
- 2016 Feb;40(1):66-73.
- doi: 10.5535/arm.2016.40.1.66
OBJECTIVE: To investigate the presence of cranial neuropathy in patients with platinum-analogue chemotherapy using electrodiagnostic evaluations. METHODS: Thirty-nine patients whose chemotherapy was completed within a month and 40 control subjects were... -
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- A Phase II Trial of Haptaplatin/5-FU and Leucovorin for Advanced Stomach Cancer
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Lee WS, Lee GW, Kim HW, Lee OJ, Lee YJ, Ko GH, Lee JS, Jang JS, Ha WS
- KMID: 1804572
- Cancer Res Treat.
- 2005 Aug;37(4):208-211.
PURPOSE: Heptaplatin (SKI-2053 R) is a new platinum analogue, with a better toxicity profile than cisplatin, and has antitumor activity even in cisplatin resistant cell lines. 5-fluoruracil (5-FU) has shown... -
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- Data Analysis for Anti-Neoplastic Chemotherapy-Related Adverse Events Reported to the Korean Pharmacovigilance Regional Network
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Lee JY, Jung JW, Kang HR, Lee SH, Kim HS, Cho SH
- KMID: 2267789
- Korean J Med.
- 2013 Oct;85(4):385-395.
BACKGROUND/AIMS: To describe the toxicity profile of anti-neoplastic agents from real clinical settings, we analyzed spontaneously reported adverse events (AEs) using data from the adverse drug reaction (ADR) reporting system... -
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- Germline and somatic mutations in homologous recombination genes among Chinese ovarian cancer patients detected using next-generation sequencing
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Zhao Q, Yang J, Li L, Cao D, Yu M, Shen K, the BGI Group
- KMID: 2413427
- J Gynecol Oncol.
- 2017 Jul;28(4):e39.
- doi: 10.3802/jgo.2017.28.e39
OBJECTIVE: To define genetic profiling of homologous recombination (HR) deficiency in Chinese ovarian cancer patients. METHODS: we have applied next-generation sequencing to detect deleterious mutations through all exons in 31 core... -
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- Relationship between Quality of Life and Nurse-led Bedside Symptom Evaluations in Patients with Chemotherapy-induced Peripheral Neuropathy
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Yoo YS, Cho OH
- KMID: 2069893
- Asian Nurs Res.
- 2014 Mar;8(1):36-41.
PURPOSE: This cross-sectional study aimed at determining the relationship between patient-reported quality of life (QOL) and nurse-led bedside evaluations of chemotherapy-induced peripheral neuropathy symptoms. METHODS: One hundred ninety-five patients treated at... -
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- Combination Chemotherapy with 5-Fluorouracil and Heptaplatin as First-line Treatment in Patients with Advanced Gastric Cancer
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Min YJ, Bang SJ, Shin JW, Kim DH, Park JH, Kim GY, Ko BK, Choi DH, Cho HR
- KMID: 1786814
- J Korean Med Sci.
- 2004 Jun;19(3):369-373.
- doi: 10.3346/jkms.2004.19.3.369
Heptaplatin is a recently developed platinum derivative. This agent has been reported to have a response rate of 17% as a single agent, and tolerable toxicity in the treatment of... -
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