- Biomarker-guided targeted therapy in platinum-resistant ovarian cancer (AMBITION; KGOG 3045): a multicentre, open-label, five-arm, uncontrolled, umbrella trial
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Lee JY, Kim BG, Kim JW, Lee JB, Park E, Joung JG, Kim S, Choi CH, Kim HS, on behalf of Korean Gynecologic Oncology Group (KGOG) investigators
- KMID: 2537892
- J Gynecol Oncol.
- 2022 Jul;33(4):e45.
- doi: 10.3802/jgo.2022.33.e45
Objective Management of heavily pre-treated platinum-resistant ovarian cancer remains a therapeutic challenge. Outcomes are poor with non-platinum, single-agent chemotherapy (CT); however, molecularly targeted anticancer therapies provide new options. Methods This open-label, investigator-initiated, phase... -
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- Efficacy and safety of intravenous administration of high-dose selenium for preventing chemotherapy-induced peripheral neuropathy in platinum-sensitive recurrent ovarian, fallopian or primary peritoneal cancer: study protocol for a phase III, double-blind, randomized study
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Park SJ, Yim GW, Paik H, Lee N, Lee S, Lee M, Kim HS
- KMID: 2526148
- J Gynecol Oncol.
- 2021 Sep;32(5):e73.
- doi: 10.3802/jgo.2021.32.e73
Background The second-line chemotherapy using paclitaxel, carboplatin, and bevacizumab for treating platinum-sensitive recurrent ovarian, fallopian or primary peritoneal cancer frequently cause chemotherapy-induced peripheral neuropathy (CIPN), which is significantly associated with deterioration... -
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- Outcomes and Biomarkers of Immune Checkpoint Inhibitor Therapy in Patients with Refractory Head and Neck Squamous Cell Carcinoma: KCSG HN18-12
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Lee YG, Chang H, Keam B, Chun SH, Park J, Park KU, Shin SH, An HJ, Lee KE, Lee KW, Kim HR, Kim SB, Ahn MJ, Hwang IG
- KMID: 2518390
- Cancer Res Treat.
- 2021 Jul;53(3):671-677.
- doi: 10.4143/crt.2020.824
Purpose This study was conducted to determine the effectiveness of immune checkpoint inhibitors (ICIs) in recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC) after platinum-containing chemotherapy. We... -
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- Primary platinum resistance and its prognostic impact in patients with recurrent ovarian cancer: an analysis of three prospective trials from the NOGGO study group
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Trillsch F, Mahner S, Czogalla B, Rottmann M, Chekerov R, Braicu EI, Oskay-Öczelik G, Wimberger P, Richter R, Sehouli J
- KMID: 2526394
- J Gynecol Oncol.
- 2021 May;32(3):e37.
- doi: 10.3802/jgo.2021.32.e37
Objective: Patients with platinum-resistant ovarian cancer (PROC) have a high need for reliable prognostic markers. Since significance of primary platinum resistance (PPR) versus secondary platinum resistance (SPR) was identified for... -
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- Serum lactate dehydrogenase is a possible predictor of platinum resistance in ovarian cancer
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Ikeda A, Yamaguchi K, Yamakage H, Abiko K, Satoh-Asahara N, Takakura K, Konishi I
- KMID: 2511211
- Obstet Gynecol Sci.
- 2020 Nov;63(6):709-718.
- doi: 10.5468/ogs.20117
Objective The need for tailoring ovarian cancer treatments to individual patients is increasing. This study aimed to evaluate the prognostic value of pretreatment laboratory test data for predicting the response... -
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- The post-progression survival of patients with recurrent or persistent ovarian clear cell carcinoma: results from a randomized phase III study in JGOG3017/GCIG
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Kondo E, Tabata T, Suzuki N, Aoki D, Yahata H, Kotera Y, Tokuyama O, Fujiwara K, Kimura E, Terauchi F, Sumi T, Okamoto A, Yaegashi N, Enomoto T, Sugiyama T
- KMID: 2512059
- J Gynecol Oncol.
- 2020 Nov;31(6):e94.
- doi: 10.3802/jgo.2020.31.e94
Objective: In this study we sought to investigate the clinical factors that affect postprogression survival (PPS) in patients with recurrent or persistent clear cell carcinoma (CCC). We utilized the JGOG3017/Gynecological Cancer... -
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- Diffuse reflection characterization and visible light mediated antibacterial effect of Pt-TiO2 nanotubes
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Moon KS, Bae JM, Oh S
- KMID: 2504116
- Korean J Dent Mater.
- 2020 Jun;47(2):93-104.
- doi: 10.14815/kjdm.2020.47.2.93
The purpose of this study was to fabricate platinum (Pt), one of the plasmonic nanoparticles that induces localized surface plasmon resonance (LSPR) effects caused by the pairing of plasmon with... -
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- Real world effectiveness and safety of pegylated liposomal doxorubicin in platinum-sensitive recurrent ovarian, fallopian, or primary peritoneal cancer: a Korean multicenter retrospective cohort study
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Park SJ, Kim J, Kim HS, Lee JW, Chang HK, Lee KH, Kim DY, Kim S, Chang SJ, Han SS, Park SY, Shim SH
- KMID: 2470868
- J Gynecol Oncol.
- 2020 Mar;31(2):e15.
- doi: 10.3802/jgo.2020.31.e15
OBJECTIVE: To evaluate the effectiveness and safety of the combination of pegylated liposomal doxorubicin with carboplatin (CD) compared with those of carboplatin and paclitaxel (CP) for platinum-sensitive recurrent ovarian, fallopian,... -
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- Potential predictors for chemotherapeutic response and prognosis in epithelial ovarian, fallopian tube and primary peritoneal cancer patients treated with platinum-based chemotherapy
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Jeerakornpassawat D, Suprasert
- KMID: 2467932
- Obstet Gynecol Sci.
- 2020 Jan;63(1):55-63.
- doi: 10.5468/ogs.2020.63.1.55
OBJECTIVE: This study aimed to investigate the potential predictive factors for platinum resistance and poor prognosis in epithelial ovarian, fallopian tube, and primary peritoneal cancer treated with platinum-based chemotherapy. METHODS: Medical... -
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- Involved-field radiation therapy for selected cases of recurrent ovarian cancer
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Kim N, Chang JS, Kim SW, Kim GM, Lee JY, Kim YB
- KMID: 2457149
- J Gynecol Oncol.
- 2019 Sep;30(5):e67.
- doi: 10.3802/jgo.2019.30.e67
OBJECTIVES: In our institutional experience, involved-field radiation therapy (IFRT) yields favorable outcomes in patients with recurrent epithelial ovarian cancer (EOC). This retrospective study aimed to investigate the clinical benefits of... -
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- Effect of Platinum-Based Chemotherapy on PD-L1 Expression on Tumor Cells in Non-small Cell Lung Cancer
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Shin J, Chung JH, Kim SH, Lee KS, Suh KJ, Lee JY, Kim JW, Lee JO, Kim JW, Kim YJ, Lee KW, Kim JH, Bang SM, Lee JS
- KMID: 2454300
- Cancer Res Treat.
- 2019 Jul;51(3):1086-1097.
- doi: 10.4143/crt.2018.537
PURPOSE: Programmed death-1 (PD-1)/PD-1 ligand (PD-L1) axis blockades have revolutionized the treatment of advanced non-small cell lung cancer (NSCLC). We assessed the effect of platinum-based chemotherapy on tumor PD-L1 expression... -
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- Retrospective study of combination chemotherapy with etoposide and ifosfamide in patients with heavily pretreated recurrent or persistent epithelial ovarian cancer
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Shin W, Lee HJ, Yang SJ, Paik ES, Choi HJ, Kim TJ, Choi CH, Lee JW, Bae DS, Kim BG
- KMID: 2416123
- Obstet Gynecol Sci.
- 2018 May;61(3):352-358.
- doi: 10.5468/ogs.2018.61.3.352
OBJECTIVE: This retrospective study is to evaluate the efficacy and toxicity of combination chemotherapy with etoposide and ifosfamide (ETI) in the management of pretreated recurrent or persistent epithelial ovarian cancer... -
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- Upper eyelid platinum weight placement for the treatment of paralytic lagophthalmos: A new plane between the inner septum and the levator aponeurosis
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Oh TS, Min K, Song SY, Choi JW, Koh KS
- KMID: 2413017
- Arch Plast Surg.
- 2018 May;45(3):222-228.
- doi: 10.5999/aps.2017.01599
BACKGROUND: The most common surgical treatment for paralytic lagophthalmos is the placement of a weight implant in the upper eyelid; however, this technique confers the risks of implant visibility, implant... -
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- Pemetrexed Continuation Maintenance versus Conventional Platinum-Based Doublet Chemotherapy in EGFR-Negative Lung Adenocarcinoma: Retrospective Analysis
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Paik SS, Hwang IK, Park MJ, Lee SH
- KMID: 2420603
- Tuberc Respir Dis.
- 2018 Apr;81(2):148-155.
- doi: 10.4046/trd.2017.0090
BACKGROUND: Although targeted therapy and immuno-oncology have shifted the treatment paradigm for lung cancer, platinum-based combination is still the standard of care for advanced non-small cell lung cancer (NSCLC). Pemetrexed... -
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- ERCC1 Expression-Based Randomized Phase II Study of Gemcitabine/Cisplatin Versus Irinotecan/Cisplatin in Patients with Advanced Non-small Cell Lung Cancer
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Han JY, Lee GK, Lim KY, Lee YJ, Nam BH, Lee JS
- KMID: 2388313
- Cancer Res Treat.
- 2017 Jul;49(3):678-687.
- doi: 10.4143/crt.2016.365
PURPOSE: We evaluated the clinical utility of excision repair cross-complementation group 1 (ERCC1) expression as a predictive biomarker for platinum-based chemotherapy in advanced non-small cell lung cancer (NSCLC). MATERIALS AND METHODS:... -
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- Reactive Oxygen Species Modulator 1 (Romo1) Predicts Poor Outcomes in Advanced Non-small Cell Lung Cancer Patients Treated with Platinum-Based Chemotherapy
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Lee SH, Choi SI, Lee JS, Kim CH, Jung WJ, Lee EJ, Min KH, Hur GY, Lee SH, Lee SY, Kim JH, Lee SY, Shin C, Shim JJ, Kang KH, In KH
- KMID: 2367511
- Cancer Res Treat.
- 2017 Jan;49(1):141-149.
- doi: 10.4143/crt.2016.133
PURPOSE: Reactive oxygen species modulator 1 (Romo1) is a key mediator of intracellular reactive oxygen species production. However, examination of the clinical usefulness of Romo1 in cancers has been limited.... -
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- Delay of the Blink Reflex in Patients Receiving Platinum-Analogue Chemotherapy
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Park KY, Park YS, Park YH, Chang HJ, Cho ES, Kim SH, Kim WJ
- KMID: 2155167
- Ann Rehabil Med.
- 2016 Feb;40(1):66-73.
- doi: 10.5535/arm.2016.40.1.66
OBJECTIVE: To investigate the presence of cranial neuropathy in patients with platinum-analogue chemotherapy using electrodiagnostic evaluations. METHODS: Thirty-nine patients whose chemotherapy was completed within a month and 40 control subjects were... -
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- Pemetrexed Singlet Versus Nonpemetrexed-Based Platinum Doublet as Second-Line Chemotherapy after First-Line Epidermal Growth Factor Receptor (EGFR) Tyrosine Kinase Inhibitor Failure in Non-small Cell Lung Cancer Patients with EGFR Mutations
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Park S, Keam B, Kim SH, Kim KH, Kim YJ, Kim JS, Kim TM, Lee SH, Kim DW, Lee JS, Heo DS
- KMID: 2403380
- Cancer Res Treat.
- 2015 Oct;47(4):630-637.
- doi: 10.4143/crt.2014.244
PURPOSE: Platinum-based doublet chemotherapy is the treatment of choice for patients with non-small cell lung cancer (NSCLC); however, the role of a platinum-based doublet as second-line therapy after failure of... -
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- Platinum sensitivity and non-cross-resistance of cisplatin analogue with cisplatin in recurrent cervical cancer
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Takekuma M, Kuji S, Tanaka A, Takahashi , Abe M, Hirashima
- KMID: 2160804
- J Gynecol Oncol.
- 2015 Jul;26(3):185-192.
- doi: 10.3802/jgo.2015.26.3.185
OBJECTIVE: The concept of platinum sensitivity and cross-resistance among platinum agents are widely known in the management of recurrent ovarian cancer. The aim of this study was to evaluate two... -
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- Characterization and bacterial anti-adherent effect on modified PMMA denture acrylic resin containing platinum nanoparticles
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Nam KY
- KMID: 2118232
- J Adv Prosthodont.
- 2014 Jun;6(3):207-214.
- doi: 10.4047/jap.2014.6.3.207
PURPOSE: This study characterized the synthesis of a modified PMMA (Polymethyl methacrylate) denture acrylic loading platinum nanoparticles (PtN) and assessed its bacterial inhibitory efficacy to produce novel antimicrobial denture base... -
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