- Co-activation of Gi and Gq proteins exerts synergistic effect on human platelet aggregation through activation of phospholipase C and Ca2+ signalling pathways
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Shah BH, Siddiqui A, Qureshi KA, Khan M, Rafi S, Ujan VA, Yakoob MY, Rasheed H, Saeed SA
- KMID: 755026
- Exp Mol Med.
- 1999 Mar;31(1):42-46.
Our previous studies have shown that subthreshold concentrations of two platelet agonists exert synergistic effects on platelet aggregation. Here we studied the mechanism of synergistic interaction of 5-hydroxytryptamine (5-HT) and epinephrine mediated platelet... -
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- The effect of experimental trypsin on the regeneration of hyaline articular cartilage
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Han CD, Kang HJ
- KMID: 1113850
- Yonsei Med J.
- 1990 Jun;31(2):103-109.
- doi: 10.3349/ymj.1990.31.2.103
There is evidence from other studies that some degree of cartilage healing may take place after the initiation of an inflammatory response. It is postulated that the induction of the... -
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- Effects of Calcium Channel Blockers and Insulin on the Platelet Function in Patients with Diabetes Mellitus
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Lee YS, Hahm KS, Lee SY
- KMID: 693024
- Yonsei Med J.
- 1986 Jun;27(2):132-137.
- doi: 10.3349/ymj.1986.27.2.132
Platelet aggregability was compared between platelets isolated from normal subjects and patients with diabetes mellitus in order to evaluate the effects of calcium channel blockers and insulin on the platelet... -
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- The Impact of Generic Clopidogrel Bisulfate on Platelet Inhibition in Patients with Coronary Artery Stents: Results of the ACCEL-GENERIC Study
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Jeong YH, Koh JS, Kang MK, Ahn YJ, Kim IS, Park Y, Hwang SJ, Kwak CH, Hwang JY
- KMID: 1785672
- Korean J Intern Med.
- 2010 Jun;25(2):154-161.
- doi: 10.3904/kjim.2010.25.2.154
BACKGROUND/AIMS: In patients with coronary artery stents, the cost of clopidogrel has been cited as a factor in the premature discontinuation of therapy. Thus, the introduction of lower-cost generic clopidogrel... -
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- Effect of Nitric Oxide on the Cryopreservation of Platelets
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Lee JH, Kim JT, Cho YG
- KMID: 854846
- Korean J Lab Med.
- 2008 Apr;28(2):136-143.
- doi: 10.3343/kjlm.2008.28.2.136
BACKGROUND: To determine whether nitric oxide (NO) could inhibit activation of platelets stored in a cold or frozen state, we measured platelet P-selectin expression and platelet-bound fibrinogen in platelet-rich... -
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- Determination of the Prevalence of Aspirin and Clopidogrel Resistances in Patients with Coronary Artery Disease by using Various Platelet-function Tests
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Woo KS, Kim BR, Kim JE, Goh RY, Yu LH, Kim MH, Han JY
- KMID: 1022035
- Korean J Lab Med.
- 2010 Oct;30(5):460-468.
- doi: 10.3343/kjlm.2010.30.5.460
BACKGROUND: Dual therapy with aspirin and clopidogrel has emerged as the gold standard therapy for patients treated with drug-eluting stents (DES). However, there is variability in patients' responses to this... -
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