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Molecular mechanisms involved in human platelet aggregation by synergistic interaction of platelet-activating factor and 5-hydroxytryptamine.

Shah BH, Rasheed H, Rahman IH, Shariff AH, Khan FL, Rahman HB, Hanif S, Saeed SA

  • KMID: 1457534
  • Exp Mol Med.
  • 2001 Dec;33(4):226-233.
Our recent studies have shown that co-activation of Gq and Gi proteins by 5-hydroxytryptamine (5-HT) and adrenaline show synergism in human platelet aggregation. This study was conducted to examine the...
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Oxidative response of neutrophils to platelet-activating factor is altered during acute ruminal acidosis induced by oligofructose in heifers

Concha C, Carretta M, Alarcon P, Conejeros , Gallardo D, Hidalgo AI, Tadich N, Caceres DD, Hidalgo MA, Burgos RA

Reactive oxygen species (ROS) production is one of the main mechanisms used to kill microbes during innate immune response. D-lactic acid, which is augmented during acute ruminal acidosis, reduces platelet...
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