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Auranofin Suppresses Plasminogen Activator Inhibitor-2 Expression through Annexin A5 Induction in Human Prostate Cancer Cells

Shin DW, Kwon YJ, Ye DJ, Baek HS, Lee JE, Chun YJ

Auranofin has been developed as antirheumatic drugs, which is currently under clinical development for the treatment of chronic lymphocytic leukemia. Previous report showed that auranofin induced apoptosis by enhancement of...
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Effects of Signal Transduction Pathway in the ras-induced Cellular Transformation of Human Epithelial Cells in Culture

Jang DG, Byeon KJ, Kim CS

  • KMID: 1543523
  • J Korean Assoc Oral Maxillofac Surg.
  • 2000 Jun;26(3):254-261.
The present study has attempted to look into the mechanism of ras-induced carcinogenesis in a human epithelial cell system. Human epithelial cells immortalized with Ad12-SV40 hybrid virus were used to...
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Effects of carcinogenicity and growth ragulatory factors in human epithelial cells exposed with tobacco-specific N-nitrosamine

Kim SS, Kim CS

  • KMID: 1961227
  • J Korean Assoc Oral Maxillofac Surg.
  • 2001 Apr;27(2):129-134.
Since NNK is one of the most abundant tobacco-specific alkaloids and a strong carcinogenic nitrosamine, it has been used for evaluating a potential of carcinogenicity in the animal models. The...
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Use of real-time quantitative PCR to identify high expressed genes in head and neck squamous cell carcinoma cell lines

Lee YG, Chun SY, Lee HA, Sohn YK, Kang KS, Kim JO, Yun SM, Kim JW, Jang HJ

  • KMID: 2190364
  • J Korean Assoc Oral Maxillofac Surg.
  • 2006 Feb;32(1):69-75.
Head and neck squamous cell carcinoma(HNSCC) is the sixth most common cancer among men in the developed world affecting the tongue, pharynx, larynx and oral cavity. HNSCC is thought to...
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