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Immune Checkpoint Programmed Cell Death Protein-1 (PD-1) Expression on Bone Marrow T Cell Subsets in Patients With Plasma Cell Myeloma

Lee MY, Park CJ, Cho YU, You E, Jang S, Seo EJ, Lee JH, Yoon DH, Suh C

Background: Plasma cell myeloma (PCM) is caused by immune dysregulation. We evaluated the expression of immune checkpoint programmed cell death protein-1 (PD-1) on T cell subsets in PCM patients according...
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KRAS, NRAS, and BRAF mutations in plasma cell myeloma at a single Korean institute

Kim Y, Park SS, Min CK, Lee GD, Son J, Jo S, Han E, Han K, Kim M

Background Plasma cell myeloma (PCM) is a genetically heterogeneous disease. The genetic spectrum of PCM has been expanded to mutations such as KRAS, NRAS, and BRAF genes in the RAS-RAF-MAPK pathway....
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A Case Report of Extramedullary Myeloma Mimicking Lymphoma with Extensive Abdominal Involvement

Moon J, Hwang JA, Shin HC, Kim SS, Lee JH, Lee JE, Choi SY, Lee MY

Extramedullary myeloma refers to the presence of myeloma deposits outside the skeletal system and typically indicates a poor prognosis associated with shorter overall survival and progression- free survival. We report...
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Bleeding Tendency of a Light Chain (AL) Amyloidosis Patient Accompanied by Asymptomatic Plasma Cell Myeloma

Lee HJ, Kim JE, Park SY, Kim HK

We present a case of abrupt-onset hemorrhagic tendency in a patient with amyloidosis who also had asymptomatic plasma cell myeloma. The patient was a 66-yr-old man with no previous history...
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A Case of Intracranial Involvement in Plasma Cell Myeloma

Lee SH, Chung YY, Lim YJ, Ko SY, Choi YA, Kim YW, Lee SE, Park CW

Plasma cell myelomas generally manifest as bone or soft-tissue tumors with variable mass effects, pain, and infiltrative behavior. Extramedullary involvement occurs most commonly in the spleen, liver, lymph nodes, and...
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Immunoglobulin Isotype Switching in a Plasma Cell Myeloma Patient Treated with High-dose Chemotherapy and Hematopoietic Stem Cell Transplantation

Ham JY, Lee KM, Song KE

  • KMID: 2312183
  • Lab Med Online.
  • 2011 Jul;1(3):158-162.
A malignant plasma cell clone usually produces a single abnormal monoclonal protein with a constant isotype. However, switching of paraprotein isotype has been reported to be a transient phenomenon associated...
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Variant Burkitt-type translocation (8;22)(q24;q11) in plasma cell myeloma

Kim H, Moon HW, Hur M, Yun YM, Park CM, Lee MH

Variant Burkitt-type translocation, t(8;22)(q24;q11), is very rare in plasma cell myeloma. We report a 51-year-old male patient with plasma cell myeloma, who showed t(8;22) (q24;q11). He suffered from pelvic pain...
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SOLITARY PLASMA CELL MYELOMA ON ANTERIOR MAXILLA: A CASE REPORT

Jeong JA, Seo GE, Song JH, Park SJ

  • KMID: 2005102
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2010 Jan;32(1):77-80.
Plasma cell myeloma is malignant disease of plasma cell in the bone marrow. Myeloma accounts for about 1% of all cancers. The solitary plasma cellmyeloma is rare tumors and account...
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A case of POEMS syndrome presenting as primary adrenocortical insufficiency associated with plasma cell myeloma

Kang KY, Kim MK, Lee SO, Kwon HS, Yoon KH, Cha BY, Son HY

  • KMID: 1927306
  • Korean J Med.
  • 2004 Nov;67(Suppl 3):S761-S766.
POEMS syndrome is multisystemic disorder characterized polyneuropathy, organomegaly, endocrinopathies, monoclonal gammapathy. A 38 year-old man visited our hospital because of progressive general weakness, hyperpigmentation. We diagnosed him as idiopathic primary...
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