- Role of PKG-L-type calcium channels in the antinociceptive effect of intrathecal sildenafil
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Kim WM, Yoon MH, Cui JH
- KMID: 1110855
- J Vet Sci.
- 2010 Jun;11(2):103-106.
- doi: 10.4142/jvs.2010.11.2.103
Sildenafil increases the cyclic guanosine monophosphate (cGMP) by inhibition of a phosphodiesterase 5, thereby leading to an antinociceptive effect. The increased cGMP may exert the effect on an L-type calcium... -
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- Roles of Adenosine and Serotonin Receptors on the Antinociception of Sildenafil in the Spinal Cord of Rats
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Lee HG, Kim WM, Park CH, Yoon MH
- KMID: 1779647
- Yonsei Med J.
- 2010 Nov;51(6):960-964.
- doi: 10.3349/ymj.2010.51.6.960
PURPOSE: The phosphodiesterase 5 inhibitor sildenafil has antinociceptive effects, mediated by an increase in cGMP. This study examined the role of spinal adenosine and serotonin receptors played in the antinociceptive... -
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- Vardenafil Increases Cell Proliferation in the Dentate Gyrus through Enhancement of Serotonin Expression in the Rat Dorsal Raphe
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Kim TS, Ko IG, Sung YH, Kim SE, Kim BK, Park SK, Shin MS, Kim CJ, Yoon SJ, Kim KH
- KMID: 1783139
- J Korean Med Sci.
- 2009 Dec;24(6):1099-1104.
- doi: 10.3346/jkms.2009.24.6.1099
This study was conducted to evaluate the effects of vardenafil (Levitra), a phosphodiesterase-5 (PDE-5) inhibitor, on cell proliferation in the hippocampal dentate gyrus and on 5-hyroxytryptamine (5-HT, serotonin) synthesis and... -
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- Evaluation of the Effects of Sildenafil Citrate (Viagra) on Vertebral Artery Blood Flow in Patients with Vertebro-Basilar Insufficiency
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Bozgeyik Z, Berilgen S, Ozdemir H, Tekatas A, Ogur E
- KMID: 1118867
- Korean J Radiol.
- 2008 Dec;9(6):477-480.
- doi: 10.3348/kjr.2008.9.6.477
OBJECTIVE: To investigate the effects of sildenafil citrate (Viagra) on the vertebral artery blood flow of patients with vertebro-basilar insufficiency (VBI) using color duplex sonography (CDS). MATERIALS AND METHODS:... -
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- Detection of single nucleotide insertion of BCR/ABL region in imatinib-resistant human myelogenous leukemia SR-1 cells
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Park TH, Kwon HC, Kim HJ, Han JY, Jeong JS, Han H, Seo CY, Kwak JY, Park JI
- KMID: 1089462
- Exp Mol Med.
- 2005 Oct;37(5):507-511.
Imatinib mesylate is a selective Bcr/Abl kinase inhibitor and an effective anticancer agent for Bcr/Abl-positive chronic myelogenous leukemia. Most patients in chronic phase maintain durable responses; however, many in blast... -
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