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Synthesized TGF-beta s in RPE regulates cellular proliferation

Lee SC, Seong GJ, Kim SH, Kwon OW

Retinal pigment epithelial (RPE) cells transdifferentiate in culture, a transition which is accompanied by a shift in biological activity. The present study investigates whether transforming growth factor (TGF)-beta has the...
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Delay of Photoreceptor Cell Degeneration in rd Mice by Systemically Administered Phenyl-N-tert-butylnitrone

Kim JH, Kim JH, Yu YS, Jeong SM, Kim KW

PURPOSE: To study the effect of systemic administration of phenyl-N-tert-butylnitrone (PBN) on the degeneration of photoreceptor cells in rd mice. METHODS: PBN was injected intraperitoneally into FVB/rd mice on postnatal...
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Antiproliferative effect of mitomycin C on experimental proliferative vitreoretinopathy in rabbits

Yu HG, Chung H

To investigate the therapeutic potential of mitomycin C (MMC) in the management of proliferative vitreoretinopathy (PVR), antiproliferative effect of MMC on rabbit retinal pigment epithelial (RPE) cells, its intraocular toxicity,...
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