- Phosphatidylinositol 4-phosphate 5-kinase alpha negatively regulates nerve growth factor-induced neurite outgrowth in PC12 cells
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Liu T, Lee SY
- KMID: 2154235
- Exp Mol Med.
- 2013 Mar;45(3):e16.
Neurite outgrowth, a cell differentiation process involving membrane morphological changes, is critical for neuronal network and development. The membrane lipid, phosphatidylinositol (PI) 4,5-bisphosphate (PIP2), is a key regulator of many... -
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- N-acetyl-D-glucosamine kinase interacts with dynein light-chain roadblock type 1 at Golgi outposts in neuronal dendritic branch points
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Islam MA, Sharif SR, Lee H, Seog DH, Moon IS
- KMID: 2155431
- Exp Mol Med.
- 2015 Aug;47(8):e177.
- doi: 10.1038/emm.2015.48
N-acetylglucosamine kinase (GlcNAc kinase or NAGK) is a ubiquitously expressed enzyme in mammalian cells. Recent studies have shown that NAGK has an essential structural, non-enzymatic role in the upregulation of... -
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- Phosphatidylinositol 4-phosphate 5-kinase alpha is induced in ganglioside-stimulated brain astrocytes and contributes to inflammatory responses
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Lee SY, Kim B, Yoon S, Kim YJ, Liu T, Woo JH, Chwae YJ, Joe EH, Jou I
- KMID: 983958
- Exp Mol Med.
- 2010 Sep;42(9):662-673.
- doi: 10.3858/emm.2010.42.9.066
In brain tissue, astrocytes play defensive roles in central nervous system integrity by mediating immune responses against pathological conditions. Type I phosphatidylinositol 4-phosphate 5-kinase alpha (PIP5Kalpha) that is responsible for... -
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