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Structural basis for inhibition of protein tyrosine phosphatases by Keggin compounds phosphomolybdate and phosphotungstate.

Heo YS, Ryu JM, Park SM, Park JH, Lee HC, Hwang KY, Kim JS

  • KMID: 1380229
  • Exp Mol Med.
  • 2002 Jul;34(3):211-223.
Protein-tyrosine phosphatases (PTPs) constitute a family of receptor-like, and cytoplasmic enzymes, which catalyze the dephosphorylation of phosphotyrosine residues in a variety of receptors and signaling molecules. Together with protein tyrosine...
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