- Caffeine causes glycerophosphorylcholine accumulation through ryanodine-inhibitable increase of cellular calcium and activation of phospholipase A2 in cultured MDCK cells
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Kim DK, Jung KY
- KMID: 1109298
- Exp Mol Med.
- 1998 Sep;30(3):151-158.
Glycerophosphrylocholine (GPC) is a renal medullary compatible organic osmolyte that is derived from choline via phosphatidylcholine, which is catalyzed in part by phospholipase A2 (PLA2) and its degradation by GPC: choline phosphodiesterase (GPC:... -
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- Molecular Targets of Dietary Polyphenols with Anti-inflammatory Properties
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Yoon JH, Baek SJ
- KMID: 2158137
- Yonsei Med J.
- 2005 Oct;46(5):585-596.
- doi: 10.3349/ymj.2005.46.5.585
There is persuasive epidemiological and experimental evidence that dietary polyphenols have anti-inflammatory activity. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have long been used to combat inflammation. Recently, cyclooxygenase (COX)... -
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- Effect of Ca2+ channel blockers, external Ca2+ and phospholipase A2 inhibitors on t-butylhydroperoxide-induced lipid peroxidation and toxicity in rat liver slices
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Heo J, Kim GH, Lee KS, Go WU, Ju HJ, Park SK, Song CS, Song GA, Cho M, Yang US, Moon HK, Kim YK
- KMID: 1051573
- Korean J Intern Med.
- 1997 Jun;12(2):193-200.
OBJECTIVES: This study was undertaken to examine the effect of oxidant on lipid peroxidation and lethal cell injury in rat liver slices. METHODS: t-Butylhydroperoxide (t-BHP) was employed as a model... -
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